CAS 595-33-5: Megestrol acetate
Description:Megestrol acetate is a synthetic progestin, primarily used in the treatment of certain types of cancer and to stimulate appetite in patients experiencing weight loss due to chronic illnesses. It is a derivative of the natural hormone progesterone and exhibits anti-estrogenic properties. The chemical formula of megestrol acetate is C22H30O3, and it has a molecular weight of approximately 342.48 g/mol. This compound is typically administered orally and is known for its ability to bind to progesterone receptors, influencing various biological processes. Megestrol acetate is characterized by its lipophilic nature, which affects its absorption and distribution in the body. It is often formulated as an acetate ester, enhancing its stability and bioavailability. Common side effects may include weight gain, mood changes, and gastrointestinal disturbances. Due to its hormonal activity, it is important to monitor patients for potential interactions with other medications and underlying health conditions. Overall, megestrol acetate plays a significant role in palliative care and hormone therapy.
Formula:C24H32O4
InChI:InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1
InChI key:InChIKey=RQZAXGRLVPAYTJ-GQFGMJRRSA-N
SMILES:O=C(OC1(C(=O)C)CCC2C3C=C(C4=CC(=O)CCC4(C)C3CCC21C)C)C
- Synonyms:
- 17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione
- 17-Acetate De 17-Hydroxy-6-Methylpregna-4,6-Diene-3,20-Dione
- 17-Acetato De 17-Hidroxi-6-Metilpregna-4,6-Dieno-3,20-Diona
- 17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione
- 17-Hydroxy-6-Methylpregna-4,6-Diene-3,20-Dione 17-Acetate
- 17-Hydroxy-6-methylpregna-4,6-dien-3,20-dion-17-acetat
- 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate
- 17α-Acetoxy-6-dehydro-6-methylprogesterone
- 17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione
- 17α-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate
- See more synonyms
- 5071
- 6-Dehydro-6-methyl-17α-acetoxyprogesterone
- 6-Methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione
- 6-Methyl-17α-hydroxy-Δ6-progesterone acetate
- 6-Methyl-17α-hydroxy-Δ<sup>6</sup>-progesterone acetate
- 6-Methyl-6-dehydro-17α-acetoxyprogesterone
- 6-Methyl-Δ4,6-pregnadien-17α-ol-3,20-dione acetate
- 6-Methyl-Δ<sup>4,6</sup>-pregnadien-17α-ol-3,20-dione acetate
- Bdh 1298
- Dmap
- MGA
- Magestin
- Maygace
- Megace
- Megalia
- Megeron
- Megestat
- Megestil
- Megestin
- Megestrol acetate
- Megestryl acetate
- Nia
- Niagestin
- Nsc 71423
- Ovaban
- Ovarid
- Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, acetate
- Sc 10363
- Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-6-methyl-
