CAS 595-57-3
:Pregn-4-ene-21-carboxylic acid, 9-fluoro-11,17-dihydroxy-3-oxo-, potassium salt (1:1), (11β,17α)-
Description:
Pregn-4-ene-21-carboxylic acid, 9-fluoro-11,17-dihydroxy-3-oxo-, potassium salt (1:1), commonly known as fludrocortisone, is a synthetic corticosteroid with mineralocorticoid properties. It is characterized by its ability to enhance sodium retention and potassium excretion in the kidneys, making it useful in treating conditions like adrenal insufficiency and orthostatic hypotension. The compound features a steroid backbone with specific functional groups, including a fluorine atom at the 9-position and hydroxyl groups at the 11 and 17 positions, contributing to its biological activity. As a potassium salt, it is typically administered in a form that enhances solubility and bioavailability. Fludrocortisone is known for its potent effects on electrolyte balance and fluid retention, and it is often prescribed in low doses to minimize potential side effects, which can include hypertension and hypokalemia. Its pharmacological profile makes it an important therapeutic agent in endocrinology and related fields.
Formula:C22H31FO5·K
InChI:InChI=1S/C22H31FO5.K/c1-19-8-5-14(24)11-13(19)3-4-16-15-6-9-21(28,10-7-18(26)27)20(15,2)12-17(25)22(16,19)23;/h11,15-17,25,28H,3-10,12H2,1-2H3,(H,26,27);/t15-,16-,17-,19-,20-,21+,22-;/m0./s1
InChI key:InChIKey=AINAJZVZBITQQW-QKTJKMNOSA-N
SMILES:F[C@@]12[C@]3(C)C(=CC(=O)CC3)CC[C@]1([C@]4([C@](C)(C[C@@H]2O)[C@@](CCC(O)=O)(O)CC4)[H])[H].[K]
Synonyms:- Pregn-4-ene-21-carboxylic acid, 9-fluoro-11,17-dihydroxy-3-oxo-, potassium salt (1:1), (11β,17α)-
- SC 11927
- Pregn-4-ene-21-carboxylic acid, 9-fluoro-11,17-dihydroxy-3-oxo-, monopotassium salt, (11β,17α)-
- 17α-Pregn-4-ene-21-carboxylic acid, 9-fluoro-11β,17-dihydroxy-3-oxo-, potassium salt
- 17α-Pregn-4-ene-21-carboxylic acid, 9-fluoro-11β,17-dihydroxy-3-oxo-, monopotassium salt
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.
