CAS 595-77-7

Algestone

Description:

Algestone, with the CAS number 595-77-7, is a synthetic steroid and a derivative of progesterone. It is primarily known for its progestational activity, making it relevant in the field of reproductive health and hormone therapy. Algestone is characterized by its ability to bind to progesterone receptors, thereby influencing various physiological processes such as the menstrual cycle and pregnancy maintenance. The compound is typically administered in the form of its acetate derivative, which enhances its solubility and bioavailability. Algestone exhibits a relatively low oral bioavailability, often necessitating alternative routes of administration, such as intramuscular injections. Its pharmacological profile includes effects on the endometrium, making it useful in treating conditions related to hormonal imbalances. Additionally, Algestone's safety and efficacy have been evaluated in clinical settings, contributing to its use in certain therapeutic applications. As with many steroids, potential side effects may include hormonal imbalances and metabolic changes, warranting careful monitoring during treatment.

Formula: C₂₁H₃₀O₄

InChI: InChI=1S/C21H30O4/c1-12(22)21(25)18(24)11-17-15-5-4-13-10-14(23)6-8-19(13,2)16(15)7-9-20(17,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3/t15-,16+,17+,18-,19+,20+,21-/m1/s1

InChI key: InChIKey=CXDWHYOBSJTRJU-SRWWVFQWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(C[C@@H](O)[C@@]2(C(C)=O)O)[H]

Synonyms:

• (16Alpha)-16,17-Dihydroxypregn-4-Ene-3,20-Dione
• (16α)-16,17-Dihydroxypregn-4-ene-3,20-dione
• 16α,17-Dihydroxyprogesterone
• 16α,17α-Dihydroxypregn-4-ene-3,20-dione
• 16α,17α-Dihydroxyprogesterone
• 4-Pregnen-16α,17α-diol-3,20-dione
• Alfasone
• Alphasone
• Pregn-4-ene-3,20-dione, 16,17-dihydroxy-, (16α)-
• Pregn-4-ene-3,20-dione, 16α,17-dihydroxy-
• -Algestone

Algestone

CAS: 595-77-7

Formula: C₂₁H₃₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 346.47

Ref: 4Z-A-472

Algestone

Controlled Product

CAS: 595-77-7

Applications A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive.
References Hydorn, A., et al.: Steroids, 3, 493 (1964), Plesner, R., et al.: Acta Endorcinol., 61, 494 (1969),

Formula: C₂₁H₃₀O₄

Color and Shape: Neat

Molecular weight: 346.46

Ref: TR-A532030

Algestone

Controlled Product

CAS: 595-77-7

Algestone is a synthetic steroid that binds to and blocks the angiotensin II type I receptor (AT1). Algestone has been shown to reduce choroidal neovascularization in mouse models. The combination of algestone and estradiol benzoate has been found to be effective for the treatment of endometriosis. Algestone is not carcinogenic and was found to have no significant effect on ovarian activity in mice. The polymer used in this drug is biocompatible and can be analyzed using an analytical method.

Formula: C₂₁H₃₀O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 346.46 g/mol

Ref: 3D-FA17278

Methyl 2-Amino-6-ethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

Controlled Product

CAS: 595-77-7

Formula: C₂₁H₃₀O₄

Color and Shape: Neat

Molecular weight: 346.46

Ref: TR-M289475

Algestone

CAS: 595-77-7

Algestone is a synthetic progestational dihydroxy derivative with anti-inflammatory properties.

Formula: C₂₁H₃₀O₄

Purity: 98%

Color and Shape: White Or White Crystalline Powder

Molecular weight: 346.46

Ref: TM-T21256