CAS 59540-22-6

a,g-Dipalmitoyl-b-Lecithin

Description:

A,g-Dipalmitoyl-b-lecithin, also known as dipalmitoylphosphatidylcholine (DPPC), is a phospholipid that plays a crucial role in biological membranes, particularly in lung surfactant. It is characterized by its two palmitic acid chains, which contribute to its hydrophobic properties, and a choline head group that provides hydrophilicity. This amphiphilic nature allows DPPC to form bilayers and vesicles, making it essential for cell membrane structure and function. DPPC has a high melting point due to its saturated fatty acid chains, which influences its phase behavior and stability in various temperatures. It is commonly used in pharmaceutical formulations, particularly in drug delivery systems and liposomal formulations, due to its biocompatibility and ability to encapsulate hydrophobic drugs. Additionally, DPPC is studied for its role in pulmonary surfactant therapy, as it reduces surface tension in the alveoli, aiding in respiratory function. Its CAS number, 59540-22-6, is used for identification in chemical databases and regulatory contexts.

Formula: C₄₀H₈₀NO₇P

InChI: InChI=1/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(49-50(44,45)48-35-34-41(3,4)5)37-47-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3

InChI key: InChIKey=CYFBGSYWHRQAIT-UHFFFAOYSA-N

SMILES: C(OP(OCC[N+](C)(C)C)(=O)[O-])(COC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

Synonyms:

• (4-Oxido-9-oxo-6-(palmitoylmethyl)-3,5,8-trioxa-4-phosphatetracosyl)trimethylammonium 4-oxide
• 1,3-Bis(Hexadecanoyloxy)Propan-2-Yl 2-(Trimethylammonio)Ethyl Phosphate
• 1,3-Dipalmitoyl-2-phosphatidylcholine
• 1,3-Dipalmitoylphosphatidylcholine
• 1,3-Dppc
• 3,5,8-Trioxa-4-phosphatetracosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-6-(((1-oxohexadecyl)oxy)methyl)-, hydroxide, inner salt, 4-oxide
• 3,5,8-Trioxa-4-phosphatetracosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-9-oxo-6-[[(1-oxohexadecyl)oxy]methyl]-, inner salt, 4-oxide
• β-Dipalmitoyllecithin
• [[2-(Trimethylaminio)ethoxy][2-(hexadecanoyloxy)-1-(hexadecanoyloxymethyl)ethoxy]phosphinic acid]anion
• alpha,beta-dipalmitoyl-beta-lecithin monohydrate
• 1,3-Dipalmitoyl-glycero-2-phosphocholine
• Einecs 261-800-5
• N,N,N-Trimethyl-2-[[[[1,3-bis(hexadecanoyloxy)propan-2-yl]oxy]oxylatophosphinyl]oxy]ethan-1-aminium

1,3-Dipalmitoyl-glycero-2-phosphocholine

CAS: 59540-22-6

1,3-Dipalmitoyl-glycero-2-phosphocholine is a complex compound that is used as a reagent, speciality chemical and building block in the synthesis of pharmaceuticals. It is also a useful intermediate in the synthesis of other compounds and has been used in research to study the effect of phospholipids on the stability of membranes. The CAS number for 1,3-dipalmitoyl-glycero-2-phosphocholine is 59540-22-6.

Formula: C₄₀H₈₀NO₈P

Purity: Min. 95 Area-%

Molecular weight: 734.04 g/mol

Ref: 3D-D-6053

1,3-Dipalmitoyl-glycero-2-phosphocholine

CAS: 59540-22-6

1,3-Dipalmitoyl-glycero-2-phosphocholine is a phospholipid that is present in all cell membranes. It has been studied for its role in the maintenance of membrane fluidity and integrity. 1,3-Dipalmitoyl-glycero-2-phosphocholine is an amphiphilic molecule with a hydrophobic tail and two hydrophilic heads. The molecule can be found in two conformations: symmetric (transition) and asymmetric (thermotropic). The transition to the thermotropic phase occurs at a temperature of 37 °C, when the hydrated head group diffuses away from the hydrocarbon chain. This type of lipid bilayer structure enables it to form lamellar phases at ambient temperatures, which are required for many cellular processes.

Purity: Min. 95%

Molecular weight: 734.04 g/mol

Ref: 3D-FD172098