CAS 5957-80-2

Carnosol

Description:

Carnosol is a naturally occurring compound classified as a phenolic diterpene, primarily found in the herb rosemary (Rosmarinus officinalis) and other members of the Lamiaceae family. It is known for its antioxidant, anti-inflammatory, and potential anticancer properties, making it of interest in both food science and pharmacology. Carnosol exhibits a complex structure featuring multiple rings and functional groups, contributing to its biological activity. The compound is soluble in organic solvents but has limited solubility in water. Its stability can be influenced by environmental factors such as light and temperature, which may affect its efficacy in various applications. Carnosol has been studied for its ability to modulate various signaling pathways, including those involved in oxidative stress and inflammation, suggesting potential therapeutic uses. Additionally, it is often explored for its role in food preservation due to its antimicrobial properties. Overall, carnosol represents a significant compound in natural product chemistry with promising health benefits and applications.

Formula: C₂₀H₂₆O₄

InChI: InChI=1/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13?,14?,20-/m1/s1

InChI key: InChIKey=XUSYGBPHQBWGAD-PJSUUKDQSA-N

SMILES: O=C1[C@@]23C=4C([C@](C[C@]2(C(C)(C)CCC3)[H])(O1)[H])=CC(C(C)C)=C(O)C4O

Synonyms:

• (4aR,9S,10aS)-1,3,4,9,10,10a-Hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-2H-9,4a-(epoxymethano)phenanthren-12-one
• (5Beta)-11,12-Dihydroxy-7,20-Epoxyabieta-8(14),9(11),12-Trien-20-One
• (5Beta,7Alpha)-11,12-Dihydroxy-7,20-Epoxyabieta-8,11,13-Trien-20-One
• (5Xi)-11,12-Dihydroxy-7,20-Epoxyabieta-8(14),9(11),12-Trien-20-One
• 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)-
• 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-(4aalpha,9alpha,10abeta))-
• 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, [4aR-(4aα,9α,10aβ)]-
• Ccris 7122
• Hsdb 7680
• NSC 39143
• Picrosalvin
• Podocarpa-8,11,13-trien-17-oic acid, 7β,11,12-trihydroxy-13-isopropyl-, 17,7-lactone
• CARNOSOL(RG)
• CARNOSOL USP/EP/BP
• 1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE
• 1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE
• Carnosol, 98%, from Rosemarinus officinalis
• 1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE
• CARNOSOL

Carnosol

CAS: 5957-80-2

Carnosol analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₂₀H₂₆O₄

Purity: (HPLC) ≥90%

Color and Shape: Powder

Molecular weight: 330.43

Ref: 11-3735

Carnosol

CAS: 5957-80-2

Formula: C₂₀H₂₆O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 330.4180

Ref: IN-DA003OPQ

Carnosol

CAS: 5957-80-2

Carnosol

Formula: C₂₀H₂₆O₄

Purity: 98.67% (Typical Value in Batch COA)

Color and Shape: solid

Molecular weight: 330.42g/mol

Ref: 54-BIM1253

Carnosol

Controlled Product

CAS: 5957-80-2

Formula: C₂₀H₂₆O₄

Color and Shape: Neat

Molecular weight: 330.42

Ref: 04-C11045600

Carnosol

CAS: 5957-80-2

Carnosol, a novel agonist of TRPA1 with an EC50 value of 12.46 uM, which exhibits anti-inflammatory, anti-nociceptive, hepatoprotective, antioxidant, anticarcinogen, anti-angiogenic, anti- invasive and antimetastatic properties. Carnosol can cause a significant decrease in both bacterial and yeast growth whilst, it may prove useful as a food antioxidant which could also contribute to the retardation of the microbial spoilage of foods; it also can inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism, it may be a potential drug against obesity-related diseases.

Formula: C₂₀H₂₆O₄

Purity: 95%~99%

Molecular weight: 330.424

Ref: BP-BP0317

Carnosol

CAS: 5957-80-2

Carnosol: antioxidant, anti-inflammatory, anti-cancer, boosts chemo. TRPA1 agonist, EC50 12.46μM.

Formula: C₂₀H₂₆O₄

Purity: 97.61% - 99.83%

Color and Shape: White To Beige Solid

Molecular weight: 330.42

Ref: TM-T6S1302

Carnosol

CAS: 5957-80-2

Formula: C₂₀H₂₆O₄

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 330.42

Ref: 7W-GP0434

Carnosol

CAS: 5957-80-2

Lactone

Formula: C₂₀H₂₆O₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 330.43

Ref: 5G-80150

CARNOSOL

CAS: 5957-80-2

Purity: 95%

Molecular weight: 330.4240112

Ref: 10-F795524

Carnosol

CAS: 5957-80-2

Formula: C₂₀H₂₆O₄

Color and Shape: Neat

Molecular weight: 330.42

Ref: TR-C184193

Carnosol

Controlled Product

CAS: 5957-80-2

Anti-cancer; anti-inflammatory

Formula: C₂₀H₂₆O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 330.42 g/mol

Ref: 3D-FC41666