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CAS 596-69-0

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18-Hydroxypregn-4-ene-3,20-dione

Description:
18-Hydroxypregn-4-ene-3,20-dione, also known as 18-hydroxycorticosterone, is a steroid hormone that plays a significant role in the regulation of various physiological processes, particularly in the adrenal cortex. It is a derivative of corticosteroids and is involved in the synthesis of aldosterone, which is crucial for electrolyte balance and blood pressure regulation. The chemical structure features a pregnane backbone with hydroxyl (-OH) groups at the 18th position, contributing to its biological activity. This compound is typically synthesized from progesterone and is characterized by its ability to bind to mineralocorticoid receptors, influencing sodium and potassium homeostasis. In terms of solubility, it is generally more soluble in organic solvents than in water, reflecting its lipophilic nature. The CAS number 596-69-0 uniquely identifies this compound in chemical databases, facilitating its study and application in research and clinical settings. Overall, 18-hydroxypregn-4-ene-3,20-dione is an important molecule in endocrinology and pharmacology, with implications for understanding adrenal function and disorders.
Formula:C21H30O3
InChI:InChI=1S/C21H30O3/c1-13(23)17-5-6-19-16-4-3-14-11-15(24)7-9-20(14,2)18(16)8-10-21(17,19)12-22/h11,16-19,22H,3-10,12H2,1-2H3/t16-,17-,18+,19+,20+,21+/m1/s1
InChI key:InChIKey=QFNCSEWPJSDMED-OFELHODLSA-N
SMILES:C(O)[C@@]12[C@]([C@]3([C@](CC1)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])(CC[C@@H]2C(C)=O)[H]
Synonyms:
  • 18-Hydroxy-progesterone
  • 18-Hydroxypregn-4-ene-3,20-dione
  • Pregn-4-ene-3,20-dione, 18-hydroxy-
  • Progesterone, 18-hydroxy-
  • 18-Hydroxyprogesterone
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Found 2 products.
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    TRC
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    18-Hydroxyprogesterone

    CAS:
    Formula:C21H30O3

    Ref: TR-TRC-H950660

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    50mg
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    10mg
    424.00€
  • 18-Hydroxyprogesterone
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    18-Hydroxyprogesterone

    Controlled Product
    CAS:

    Applications 18α-Hydroxyprogesterone is a steroid hormone related to Progesterone (P755900) which is produced by the corpus luteum. It induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
    References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),

    Formula:C21H30O3
    Color and Shape:Neat
    Molecular weight:330.46

    Ref: TR-H950660

    10mg
    436.00€
    25mg
    946.00€
    50mg
    1,624.00€