CAS 5962-19-6

(8α,9R)-10,11-Dihydrocinchonan-6′,9-diol

Description:

(8α,9R)-10,11-Dihydrocinchonan-6′,9-diol, with the CAS number 5962-19-6, is a chemical compound that belongs to the class of cinchona alkaloids, which are derived from the bark of the cinchona tree. This compound features a bicyclic structure characterized by a quinoline ring system, which is typical of many alkaloids. Its stereochemistry is defined by the specific configuration at the 8α and 9R positions, contributing to its biological activity. The presence of hydroxyl groups at the 6′ and 9 positions indicates that it has potential for hydrogen bonding, which can influence its solubility and reactivity. This compound is of interest in medicinal chemistry due to its potential pharmacological properties, including antimalarial and analgesic effects, similar to other cinchona derivatives. The diol functional groups may also play a role in its interaction with biological targets, making it a subject of study for drug development. Overall, (8α,9R)-10,11-Dihydrocinchonan-6′,9-diol exemplifies the complexity and significance of natural products in therapeutic applications.

Formula: C₁₉H₂₄N₂O₂

InChI: InChI=1S/C19H24N2O2/c1-2-12-11-21-8-6-13(12)9-18(21)19(23)15-5-7-20-17-4-3-14(22)10-16(15)17/h3-5,7,10,12-13,18-19,22-23H,2,6,8-9,11H2,1H3/t12-,13-,18-,19+/m0/s1

InChI key: InChIKey=RASAUPYEBCYZRS-BIPCEHGGSA-N

SMILES: [C@H](O)([C@]1([N@@]2C[C@H](CC)[C@](C1)(CC2)[H])[H])C=3C4=C(N=CC3)C=CC(O)=C4

Synonyms:

• (8α,9R)-10,11-Dihydrocinchonan-6′,9-diol
• 6′-Hydroxydihydrocinchonidine
• Hydrocupreine
• Cinchonan-6′,9-diol, 10,11-dihydro-, (8α,9R)-
• O6′-Demethylhydroquinine

6'-hydroxydihydrocinchonidine

CAS: 5962-19-6

'6'-hydroxydihydrocinchonidine: quinine metabolite with antimicrobial, antitumor properties; inhibits Trypanosoma brucei, Streptococcus pneumoniae.

Formula: C₁₉H₂₄N₂O₂

Purity: 99.99%

Color and Shape: Soild

Molecular weight: 312.41

Ref: TM-T77551

6'-hydroxydihydrocinchonidine

CAS: 5962-19-6

6'-hydroxydihydrocinchonidine

Purity: ≥98%

Molecular weight: 312.41g/mol

Ref: 54-BUP05347