CAS 5964-41-0

5-methyl-1-{(2R,5S)-5-[(trityloxy)methyl]-2,5-dihydrofuran-2-yl}pyrimidine-2,4(1H,3H)-dione

Description:

5-Methyl-1-{(2R,5S)-5-[(trityloxy)methyl]-2,5-dihydrofuran-2-yl}pyrimidine-2,4(1H,3H)-dione, with the CAS number 5964-41-0, is a complex organic compound characterized by its pyrimidine core and a dihydrofuran substituent. This substance features a methyl group at the 5-position of the pyrimidine ring and a trityloxy group attached to the dihydrofuran moiety, which contributes to its structural complexity and potential reactivity. The presence of the dihydrofuran ring suggests that it may exhibit unique chemical properties, such as the ability to participate in various reactions typical of cyclic ethers. The compound's stereochemistry, indicated by the (2R,5S) configuration, suggests specific spatial arrangements that could influence its biological activity and interactions with other molecules. Overall, this compound may be of interest in medicinal chemistry and organic synthesis due to its intricate structure and potential applications in drug development or as a synthetic intermediate.

Formula: C₂₉H₂₆N₂O₄

InChI: InChI=1/C29H26N2O4/c1-21-19-31(28(33)30-27(21)32)26-18-17-25(35-26)20-34-29(22-11-5-2-6-12-22,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-19,25-26H,20H2,1H3,(H,30,32,33)/t25-,26+/m0/s1

2'',3''-Dehydro-5''-O-tritylthymidine

CAS: 5964-41-0

Ref: 7W-GN3137

Zidovudine Impurity 6

CAS: 5964-41-0

Formula: C₂₉H₂₆N₂O₄

Molecular weight: 466.54

Ref: 4Z-Z-0816

2',3'-Dehydro-5'-O-tritylthymidine

CAS: 5964-41-0

2',3'-Dehydro-5'-O-tritylthymidine is an anticancer compound, which is a novel nucleoside phosphoramidite. It is synthesized from thymidine in two steps: first, the 2',3'-dideoxyribose phosphate moiety is prepared by reacting 2',3'-dideoxyribose with chloroacetic acid in the presence of triethylamine, followed by reaction with trityl chloride to form the 5' position of the thymidine. 2',3'-Dehydro-5'-O-tritylthymidine has been shown to inhibit DNA synthesis and antiviral activity.

Formula: C₂₉H₂₆N₂O₄

Purity: Min. 95%

Molecular weight: 466.54 g/mol

Ref: 3D-ND04743