CAS 59652-29-8
:Bufuralol hydrochloride
Description:
Bufuralol hydrochloride is a pharmaceutical compound primarily recognized for its use as a beta-blocker, which is effective in managing hypertension and certain cardiac conditions. It is characterized by its ability to selectively block beta-adrenergic receptors, leading to a decrease in heart rate and myocardial contractility. This compound is typically presented as a white to off-white crystalline powder, soluble in water and alcohol, which facilitates its formulation in various dosage forms. Bufuralol hydrochloride exhibits a moderate lipophilicity, influencing its pharmacokinetics and distribution within the body. Its chemical structure includes a butyl side chain and a phenolic moiety, contributing to its biological activity. The hydrochloride salt form enhances its stability and solubility, making it suitable for oral administration. As with many beta-blockers, it may have side effects, including fatigue, dizziness, and potential respiratory issues, particularly in patients with pre-existing conditions. Overall, bufuralol hydrochloride is an important agent in cardiovascular therapy, demonstrating the diverse applications of beta-adrenergic antagonists in clinical practice.
Formula:C16H23NO2·ClH
InChI:InChI=1S/C16H23NO2.ClH/c1-5-11-7-6-8-12-9-14(19-15(11)12)13(18)10-17-16(2,3)4;/h6-9,13,17-18H,5,10H2,1-4H3;1H
InChI key:InChIKey=KJBONRGCLLBWCJ-UHFFFAOYSA-N
SMILES:C(C)C1=C2C(C=C(C(CNC(C)(C)C)O)O2)=CC=C1.Cl
Synonyms:- (?à)-Bufuralol hydrochloride
- 2-Benzofuranmethanol, a-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-,hydrochloride, (?à)-
- 2-Benzofuranmethanol, α-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-, hydrochloride
- 2-Benzofuranmethanol,a-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-,hydrochloride (9CI)
- Angium
- Bufuralol hydrochloride
- Ro 3-4787 hydrochloride
- 2-Benzofuranmethanol, α-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-, hydrochloride (1:1)
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