CAS 5968-70-7

Acetyl-β-boswellic acid

Description:

Acetyl-β-boswellic acid is a pentacyclic triterpenoid compound derived from the resin of the Boswellia serrata tree, commonly known for its anti-inflammatory and analgesic properties. This compound is characterized by its unique chemical structure, which includes a fused ring system that contributes to its biological activity. Acetyl-β-boswellic acid exhibits a range of pharmacological effects, including the inhibition of pro-inflammatory mediators, making it of interest in the treatment of conditions such as arthritis and other inflammatory diseases. Its mechanism of action involves the modulation of various signaling pathways, including the inhibition of leukotriene synthesis. Additionally, this compound has shown potential in promoting apoptosis in cancer cells and may possess neuroprotective properties. Due to its natural origin, it is often considered a safer alternative to synthetic anti-inflammatory drugs. However, further research is necessary to fully understand its efficacy, optimal dosages, and potential side effects in clinical applications.

Formula: C₃₂H₅₀O₄

InChI: InChI=1S/C32H50O4/c1-19-11-14-28(4)17-18-30(6)22(26(28)20(19)2)9-10-23-29(5)15-13-25(36-21(3)33)32(8,27(34)35)24(29)12-16-31(23,30)7/h9,19-20,23-26H,10-18H2,1-8H3,(H,34,35)/t19-,20+,23-,24-,25-,26+,28-,29-,30-,31-,32-/m1/s1

InChI key: InChIKey=YJBVHJIKNLBFDX-MQURJEHKSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)([C@](C(O)=O)(C)[C@H](OC(C)=O)CC3)[H])(CC=C4[C@@]2(C)CC[C@]5(C)[C@]4([C@@H](C)[C@H](C)CC5)[H])[H]

Synonyms:

• (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
• (3Α)-3-(Acetyloxy)Urs-12-En-24-Oic Acid
• (3α)-3-Acetoxyurs-12-en-24-oic acid
• (3α,4β)-3-(Acetyloxy)urs-12-en-23-oic acid
• 3-O-Acetyl-β-boswellic acid
• 3α-Acetoxyurs-12-en-24-oic acid
• 3α-Acetyl-β-boswellic acid
• Acetyl-β-boswellic acid
• Beta-Boswellic Acid,3-Acetyl
• Urs-12-En-24-Oic Acid, 3-(Acetyloxy)-, (3Α)-
• Urs-12-en-23-oic acid, 3-(acetyloxy)-, (3α,4β)-
• Urs-12-en-24-oic acid, 3α-hydroxy-, acetate

3-O-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-O-Acetyl-beta-boswellic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₂H₅₀O₄

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 498.75

Ref: 11-2314S

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 498.7370

Ref: IN-DA003AJD

3-O-Acetyl-β-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Molecular weight: 498.74

Ref: 7W-GL8130

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-β-boswellic acid

Purity: ≥95%

Molecular weight: 498.74g/mol

Ref: 54-BUP02661

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Purity: 95%~99%

Molecular weight: 498.748

Ref: BP-BPF0530

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner.

Formula: C₃₂H₅₀O₄

Purity: 95.05% - 95.62%

Color and Shape: Solid

Molecular weight: 498.74

Ref: TM-TN1258

3-O-Acetyl-β-boswellic Acid

CAS: 5968-70-7

Formula: C₃₂H₅₀O₄

Molecular weight: 498.75

Ref: 4Z-B-134002

3-o-acetyl β-boswellic acid

CAS: 5968-70-7

Carboxylic acid with alcohol function

Formula: C₃₂H₅₀O₄

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 498.75

Ref: 5G-89152

3-O-Acetyl-β-boswellic Acid

CAS: 5968-70-7

Applications 3-O-Acetyl-beta-boswellic acid possesses anti-inflammatory potential on key inflammatory mediators, TNF-α and IL-6. Main bioactive components of frankincense which is a fragrant resin obtained from plants of the genus Boswellia, acts as a cytotoxic agents. It is also a non-competitive 5-lipoxygenase and topoisomerase I and IIa.
References Sharma, S., et al.: Bioorg. Med. Chem. Lett., 26, 695-698 (2016); Csuk, R., et al.: Tetrahedron, 71, 2025-2034 (2015); Csuk, R., et al.: Eur. J. Med. Chem., 100, 98-105 (2015);

Formula: C₃₂H₅₀O₄

Color and Shape: Neat

Molecular weight: 498.74

Ref: TR-A177770

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid is a pentacyclic triterpenoid compound, which is derived from the resin of the Boswellia serrata tree. It exhibits significant biological activity, mainly due to its anti-inflammatory properties. The mode of action primarily involves the inhibition of 5-lipoxygenase, an enzyme crucial in the biosynthesis of leukotrienes, which are mediators in inflammatory and allergic responses. Additionally, it has been shown to modulate various signaling pathways and transcription factors involved in inflammation.

Formula: C₃₂H₅₀O₄

Purity: Min. 95%

Molecular weight: 498.74 g/mol

Ref: 3D-FA65590