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CAS 59752-57-7

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1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine

Description:
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine, commonly referred to as DLPE, is a phospholipid characterized by its dual lauroyl (dodecanoyl) fatty acid chains attached to a glycerol backbone, along with a phosphoethanolamine head group. This compound is amphiphilic, possessing both hydrophilic and hydrophobic properties, which makes it an essential component in biological membranes and liposomal formulations. DLPE is known for its role in membrane fluidity and stability, contributing to the formation of lipid bilayers. It is often utilized in drug delivery systems and nanocarrier technologies due to its ability to encapsulate hydrophobic drugs and enhance their bioavailability. Additionally, DLPE can participate in various biochemical processes, including cell signaling and membrane fusion. Its structural characteristics, such as the length of the fatty acid chains and the presence of the phosphoethanolamine group, influence its physical properties, including melting point and solubility, making it a versatile compound in both research and pharmaceutical applications.
Formula:C29H58NO8P
InChI:InChI=1S/C29H58NO8P/c1-3-5-7-9-11-13-15-17-19-21-28(31)35-25-27(26-37-39(33,34)36-24-23-30)38-29(32)22-20-18-16-14-12-10-8-6-4-2/h27H,3-26,30H2,1-2H3,(H,33,34)/t27-/m1/s1
InChI key:InChIKey=ZLGYVWRJIZPQMM-HHHXNRCGSA-N
SMILES:[C@@H](COC(CCCCCCCCCCC)=O)(COP(OCCN)(=O)O)OC(CCCCCCCCCCC)=O
Synonyms:
  • 1,2-Dilauroyl-3-sn-phosphatidylethanolamine
  • 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine
  • 1,2-Dilauroyl-sn-glycero-3-phosphorylethanolamine
  • 1,2-Dilauroyl-sn-glycero-phosphoethanolamine
  • 1,2-Dilauroyl-sn-glycerophosphoethanolamine
  • 1,2-Dilauryl-sn-glycero-3-phosphoethanolamine
  • 2-Azaniumylethyl [(2R)-2,3-di(dodecanoyloxy)propyl] phosphate
  • 3-{[(2-Aminoethoxy)(Hydroxy)Phosphoryl]Oxy}-2-(Dodecanoyloxy)Propyl Dodecanoate
  • <span class="text-smallcaps">L</span>-α-Dilauroylphosphatidylethanolamine
  • <span class="text-smallcaps">L</span>-α-Dilaurylphosphatidylethanolamine
  • See more synonyms
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