CAS 59768-74-0

Boc-L-aspartic acid 4-methyl ester

Description:

Boc-L-aspartic acid 4-methyl ester is a derivative of aspartic acid, characterized by the presence of a tert-butyloxycarbonyl (Boc) protecting group on the amino group and a methyl ester at the carboxylic acid position. This compound is typically used in peptide synthesis and as an intermediate in organic synthesis due to its ability to protect functional groups during chemical reactions. It is a white to off-white solid that is soluble in organic solvents such as methanol and dichloromethane, but less soluble in water. The Boc group provides stability and protection to the amino group, allowing for selective reactions at the carboxylate site. The methyl ester enhances lipophilicity, facilitating its incorporation into various chemical processes. As with many amino acid derivatives, it may exhibit chirality, with the L-form being biologically relevant. Safety data should be consulted for handling, as with all chemical substances, to ensure proper precautions are taken during use.

Formula: C₁₀H₁₇NO₆

InChI: InChI=1/C10H17NO6/c1-10(2,3)17-9(15)11-6(8(13)14)5-7(12)16-4/h6H,5H2,1-4H3,(H,11,15)(H,13,14)/t6-/m0/s1

Synonyms:

• Boc-Asp(OMe)-OH
• Boc-Asp(OMe)-OH.DCHA
• (2S)-2-[(tert-butoxycarbonyl)amino]-4-methoxy-4-oxobutanoic acid (non-preferred name)
• Boc-Asp(OMe)-OH・DCHA

Boc-L-aspartic acid 4-methyl ester

CAS: 59768-74-0

Formula: C₁₀H₁₇NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 247.2451

Ref: IN-DA0034JZ

Boc-L-Aspartic Acid 4-Methyl Ester

CAS: 59768-74-0

Boc-L-Aspartic Acid 4-Methyl Ester

Purity: 99%

Molecular weight: 247.25g/mol

Ref: 54-OR1012522

Boc-Asp(OMe)-OH

CAS: 59768-74-0

Formula: C₁₀H₁₇NO₆

Purity: ≥ 98.0%

Color and Shape: White crystalline powder

Molecular weight: 247.25

Ref: 7W-GM5481

Boc-L-aspartic Acid β-Methyl Ester

Controlled Product

CAS: 59768-74-0

Applications Boc-L-aspartic Acid β-Methyl Ester is used to prepare isoxazoline glycoprotein IIb/IIIa antagonists. It is also used to synthesize glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.
References Xue, C., et al.: J. Med. Chem., 40, 2064 (1997); Kirkland, T., et al.: Bioorg. Med. Chem., 16, 4963 (2008)

Formula: C₁₀H₁₇NO₆

Color and Shape: Neat

Molecular weight: 247.245

Ref: TR-B621330

Boc-Asp(OMe)

CAS: 59768-74-0

Formula: C₁₀H₁₇NO₆

Purity: 95%

Color and Shape: Crystalline

Molecular weight: 247.247

Ref: 10-F221469