CAS 5978-22-3

H-Lys(Z)-OtBu . HCl

Description:

H-Lys(Z)-OtBu·HCl, also known as Z-Lysine tert-butyl ester hydrochloride, is a derivative of the amino acid lysine, modified to include a tert-butyl ester protecting group and a benzyloxycarbonyl (Z) group. This compound is typically used in peptide synthesis and organic chemistry as a protected form of lysine, which allows for selective reactions without interfering with the amino group. The presence of the tert-butyl ester enhances the compound's stability and solubility in organic solvents, making it suitable for various synthetic applications. The hydrochloride salt form indicates that the compound is protonated, which can improve its solubility in aqueous solutions. H-Lys(Z)-OtBu·HCl is characterized by its ability to undergo deprotection under specific conditions, allowing for the release of the free amino group for further reactions. Its structural features contribute to its utility in the synthesis of peptides and other complex organic molecules, making it a valuable reagent in medicinal chemistry and biochemistry.

Formula: C₁₈H₂₉ClN₂O₄

InChI: InChI=1/C18H28N2O4.ClH/c1-18(2,3)24-16(21)15(19)11-7-8-12-20-17(22)23-13-14-9-5-4-6-10-14;/h4-6,9-10,15H,7-8,11-13,19H2,1-3H3,(H,20,22);1H/t15-;/m0./s1

SMILES: CC(C)(C)OC(=O)[C@H](CCCCN=C(O)OCc1ccccc1)N.Cl

Synonyms:

• H-Lys(Z)-OBut*HCl
• N-e-CBZ-L-Lys-O-tert-Bu HCl
• (2S)-6-{[(benzyloxy)carbonyl]amino}-1-tert-butoxy-1-oxohexan-2-aminium chloride
• H-Lys(Z)-OtBu・HCl

H-Lys(Z)-OtBu · HCl

CAS: 5978-22-3

Bachem ID: 4000312.

Formula: C₁₈H₂₈N₂O₄·HCl

Purity: > 99%

Color and Shape: White

Molecular weight: 372.89

Ref: 01-4000312

H-LYS(Z)-OTBU HCL

CAS: 5978-22-3

Formula: C₁₈H₂₉ClN₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 372.8869

Ref: IN-DA00EARY

H-Lys(Z)-OtBu.HCl

CAS: 5978-22-3

H-Lys(Z)-OtBu.HCl

Purity: 95%

Molecular weight: 372.89g/mol

Ref: 54-OR1036502

H-L-Lys(Z)-OtBu hydrochloride

CAS: 5978-22-3

Molecular weight: 372.88

Ref: 7W-GM9431

H-Lys(Z)-OtBu HCl

CAS: 5978-22-3

Formula: C₁₈H₂₉ClN₂O₄

Purity: 95%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 372.89

Ref: 10-F213710

H-Lys(z)-OtBu Hydrochloride

Controlled Product

CAS: 5978-22-3

Applications H-Lys(z)-OtBu Hydrochloride is an inhibitor of dihydrofolate reductase.
References Kempton, R. J., et al.: J. Med. Chem., 25, 475 (1982)

Formula: C₁₈H₂₉ClN₂O₄

Color and Shape: Off-White

Molecular weight: 372.89

Ref: TR-L488850

Ne-Z-L-lysine tert-butyl ester hydrochloride

CAS: 5978-22-3

Ne-Z-L-lysine tert-butyl ester hydrochloride is a multidrug that inhibits the activity of the P-glycoprotein (Pgp) transporter. This drug is an antigen that can be used as a marker for cytostatic drugs, and it can be used in radionuclide localization. Ne-Z-L-lysine tert-butyl ester hydrochloride has been shown to have cytostatic effects on malignant cells, but its cytotoxicity varies depending on the type of cancer cell. Ne-Z-L-lysine tert-butyl ester hydrochloride has also been shown to be degradable and to possess conjugates with antibodies, which makes it useful for treating some types of cancers. Ne-Z-L-lysine tert-butyl ester hydrochloride is not active against resistant cells such as those expressing Pgp or MRP1 proteins.

Formula: C₁₈H₂₈N₂O₄·HCl

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 372.89 g/mol

Ref: 3D-FN47294