CAS 59826-22-1

8-Hydroxycarteolol

Description:

8-Hydroxycarteolol is a synthetic compound classified as a beta-blocker, primarily used in the treatment of glaucoma and ocular hypertension. It is characterized by its ability to reduce intraocular pressure by decreasing the production of aqueous humor in the eye. The chemical structure of 8-Hydroxycarteolol features a hydroxyl group at the 8-position of the carteolol molecule, which contributes to its pharmacological properties. This compound exhibits both beta-adrenergic blocking activity and intrinsic sympathomimetic activity, making it effective in managing cardiovascular conditions as well. In terms of solubility, it is generally soluble in organic solvents and has limited solubility in water. The compound's safety profile and efficacy have been evaluated in clinical settings, highlighting its role in ophthalmic therapies. As with any medication, potential side effects may include ocular irritation or systemic effects related to beta-adrenergic blockade. Overall, 8-Hydroxycarteolol represents a significant advancement in the pharmacological management of eye conditions.

Formula: C₁₆H₂₄N₂O₄

InChI: InChI=1S/C16H24N2O4/c1-16(2,3)17-8-10(19)9-22-13-6-5-12(20)15-11(13)4-7-14(21)18-15/h5-6,10,17,19-20H,4,7-9H2,1-3H3,(H,18,21)

InChI key: InChIKey=TVZJLAKRXHGVOK-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)(C)C)O)C1=C2C(=C(O)C=C1)NC(=O)CC2

Synonyms:

• 2(1H)-Quinolinone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-8-hydroxy-
• 5-[3-(tert-butylamino)-2-hydroxypropoxy]-8-hydroxy-3,4-dihydroquinolin-2(1H)-one
• 5-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-8-hydroxy-2(1H)-quinolinone
• 8-Hydroxycarteolol

8-Hydroxy Carteolol

CAS: 59826-22-1

Formula: C₁₆H₂₄N₂O₄

Molecular weight: 308.38

Ref: 4Z-C-154017

8-Hydroxycarteolol Hydrochloride

Controlled Product

CAS: 59826-22-1

Formula: C₁₆H₂₄N₂O₄·HCl

Color and Shape: Neat

Molecular weight: 344.83

Ref: TR-H926035

8-Hydroxycarteolol-D9 Hydrochloride

Controlled Product

CAS: 59826-22-1, 60712-33-6

Formula: C₁₆H₁₅D₉N₂O₄·(HCl)

Color and Shape: Neat

Molecular weight: 353.89

Ref: TR-H926036

8-Hydroxycarteolol

Controlled Product

CAS: 59826-22-1

Formula: C₁₆H₂₄N₂O₄

Color and Shape: Neat

Molecular weight: 308.371

Ref: TR-H926030