CAS 59854-12-5

tert-butyl 4-hydroxybutanoate

Description:

Tert-butyl 4-hydroxybutanoate, with the CAS number 59854-12-5, is an ester derived from the reaction of tert-butyl alcohol and 4-hydroxybutanoic acid. This compound typically appears as a colorless to pale yellow liquid and is characterized by its pleasant, fruity odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic tert-butyl group. The presence of the hydroxy group contributes to its reactivity, making it a potential candidate for various chemical reactions, including esterification and transesterification. Tert-butyl 4-hydroxybutanoate is often utilized in organic synthesis and may serve as an intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Its stability under standard conditions makes it a useful compound in laboratory settings, although care should be taken to handle it properly, as with all chemical substances, to avoid any potential hazards associated with its use.

Formula: C₈H₁₆O₃

InChI: InChI=1/C8H16O3/c1-8(2,3)11-7(10)5-4-6-9/h9H,4-6H2,1-3H3

SMILES: CC(C)(C)OC(=O)CCCO

Synonyms:

• Butanoic acid, 4-hydroxy-, 1,1-dimethylethyl ester

Tert-Butyl 4-Hydroxybutyrate

CAS: 59854-12-5

Formula: C₈H₁₆O₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 160.2108

Ref: IN-DA003UK7

Tert-Butyl 4-hydroxybutanoate

CAS: 59854-12-5

Tert-Butyl 4-hydroxybutanoate is an important raw material for organic synthesis.

Formula: C₈H₁₆O₃

Purity: 98.09%

Color and Shape: Solid

Molecular weight: 160.21

Ref: TM-T84031

tert-Butyl 4-hydroxybutyrate

CAS: 59854-12-5

Molecular weight: 160.21

Ref: 7W-GM1263

tert-Butyl-4-hydroxybutyrate

CAS: 59854-12-5

tert-Butyl-4-hydroxybutyrate

Formula: C₈H₁₆O₃

Purity: 98%

Color and Shape: light yellow liquid

Molecular weight: 160.21g/mol

Ref: 54-OR313037

tert-Butyl-4-hydroxybutyrate

CAS: 59854-12-5

Formula: C₈H₁₆O₃

Purity: 95%

Color and Shape: Liquid

Molecular weight: 160.213

Ref: 10-F302684

tert-Butyl 4-Hydroxybutanoate

Controlled Product

CAS: 59854-12-5

Applications tert-Butyl 4-Hydroxybutanoate is used as a reagent in the synthesis of theranostic vitamin-linker-taxoid conjugates. tert-Butyl 4-Hydroxybutanoate is also used as a reagent in the synthesis of teroxazoles as α-helix mimetics.
References Vineberg, J.G., et al.: J. Med. Chem., 58, 2406 (2015); Pinto Gomes, C., et al.: Eur. J. Org. Chem., 2012, 3270 (2012)

Formula: C₈H₁₆O₃

Color and Shape: Neat

Molecular weight: 160.21

Ref: TR-B693210

tert-Butyl 4-hydroxybutyrate

Controlled Product

CAS: 59854-12-5

Tert-butyl 4-hydroxybutyrate is an organic compound that is the tert-butyl ester of 4-hydroxybutyric acid. It can be synthesized by a regioselective synthesis from 3-hydroxypropanoic acid and butyric acid. Tert-butyl 4-hydroxybutyrate can also be synthesized by tethering hydroxylamines to prodrug form of tert-butanol. Tert-Butyl 4-hydoxybutyrate is a prodrug form of the drug, Terbumost, which is an esterase inhibitor used to treat ulcerative colitis. This drug has been shown to selectively inhibit the activity of esterases in the gastrointestinal tract and thereby reduce inflammation by inhibiting prostaglandin synthesis. This inhibition occurs at low doses and has little effect on other enzymes such as cytochrome P450 or glutathione reductase.

Formula: C₈H₁₆O₃

Purity: Min. 95%

Molecular weight: 160.21 g/mol

Ref: 3D-FB157013