CAS 59864-04-9

Sulindac Sulfone

Description:

Sulindac sulfone, with the CAS number 59864-04-9, is a non-steroidal anti-inflammatory drug (NSAID) that is a metabolite of sulindac, primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing inflammation and pain. Sulindac sulfone is typically administered in oral form and is known for its relatively low gastrointestinal toxicity compared to other NSAIDs. The compound is often utilized in the treatment of conditions such as arthritis and other inflammatory disorders. Its chemical structure includes a sulfinyl group, which contributes to its pharmacological activity. Additionally, sulindac sulfone has been studied for its potential chemopreventive effects in certain types of cancer, particularly colorectal cancer. As with any medication, it is essential to consider potential side effects and contraindications, and its use should be guided by a healthcare professional.

Formula: C₂₀H₁₇FO₄S

InChI: InChI=1/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9+

Synonyms:

• 5-Fluoro-2-methy l-1-((4-(methylsulfonyl)phenyl)methylene)-1H-indene-3-acetic acid
• 1H-Indene-3-acetic acid, 5-fluoro-2-methy l-1-((4-(methylsulfonyl)phenyl)methylene)-
• [(1Z)-5-fluoro-2-methyl-1-{[4-(methylsulfonyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid
• [(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfonyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid

5-Fluoro-2-methyl-1-[[4-(methylsulfonyl)phenyl]methylene]-1H-indene-3-acetic acid

CAS: 59864-04-9

Formula: C₂₀H₁₇FO₄S

Purity: 95%

Molecular weight: 372.4100

Ref: IN-DA00E93W

Sulindac sulfone

CAS: 59864-04-9

Formula: C₂₀H₁₇FO₄S

Molecular weight: 372.41

Ref: 7W-GL6393

Sulindac sulfone

CAS: 59864-04-9

Sulindac sulfone

Purity: ≥98%

Molecular weight: 372.41g/mol

Ref: 54-BUP10462

Sulindac sulfone

CAS: 59864-04-9

Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. Sulindac sulfone is an inhibitor of aldose reductase (IC50 =367 nM).

Formula: C₂₀H₁₇FO₄S

Purity: 98.2% - 98.83%

Color and Shape: Solid

Molecular weight: 372.41

Ref: TM-T23403

Sulindac Sulfone

Controlled Product

CAS: 59864-04-9

Formula: C₂₀H₁₇FO₄S

Color and Shape: Neat

Molecular weight: 372.41

Ref: TR-S699323