CAS 59867-24-2

N1,O2''-Dimethyladenosine Monohydriodide

Description:

N1,O2-Dimethyladenosine Monohydriodide is a modified nucleoside, specifically an analog of adenosine, which is a fundamental component of nucleic acids. This compound features two methyl groups attached to the nitrogen at position 1 and the oxygen at position 2 of the adenine base, which can influence its biological activity and interactions with nucleic acid structures. The presence of a monohydriodide indicates that the compound is associated with one iodide ion, which can affect its solubility and reactivity. Typically, such modifications can enhance the stability of the nucleoside against enzymatic degradation and may alter its affinity for various biological targets, including receptors and enzymes. N1,O2-Dimethyladenosine Monohydriodide is often utilized in biochemical research, particularly in studies involving RNA and DNA interactions, as well as in the development of therapeutic agents. Its unique structural characteristics make it a valuable tool in understanding nucleic acid function and regulation.

Formula: C₁₂H₁₈IN₅O₄

Synonyms:

• N1,O2''-Dimethyladenosine Monohydriodide

N1,O2'-Dimethyladenosine-d3 Monohydriodide

Controlled Product

CAS: 59867-24-2, 91101-00-7

Applications N1,O2'-Dimethyladenosine-d3 Monohydriodide is an intermediate in the synthesis of N6,O2'-Dimethyladenosine-d3 (D447417). N6,O2'-Dimethyladenosine-d3 is an isotopic analog of N6,O2'-Dimethyladenosine (D447415), a naturally occurring modified nucleoside in RNA. It was reported in the preparation of alkylated adenosines as antihypertensive agents.
References Yamada, T., Kageyama, K.: Eur. Pat. Appl. (1988), EP 269574 A2 19880601; Aduri, R., et al.: J. Chem. Theory Comput., 3, 1464 (2007)

Formula: C₁₂D₃H₁₅N₅O₄·I

Color and Shape: Neat

Molecular weight: 426.225

Ref: TR-D447414

N1,O2'-Dimethyladenosine Monohydriodide

Controlled Product

CAS: 59867-24-2

Formula: C₂₁H₂₃ClFNO₃

Color and Shape: Neat

Molecular weight: 391.864

Ref: TR-D447411

N1,O2'-Dimethyladenosine-d3 Monohydriodide

Controlled Product

CAS: 59867-24-2, 91101-00-7

Applications N1,O2'-Dimethyladenosine Monohydriodide-d3, is the labeled a analogue of N1,O2'-Dimethyladenosine Monohydriodide (D447411), is an intermediate useful in the synthesis of N6,O2'-Dimethyladenosine (D447415), which is naturally occurring modified nucleoside in RNA. It was reported in the preparation of alkylated adenosines as antihypertensive agents.
References Yamada, T., Kageyama, K.: Eur. Pat. Appl. (1988), EP 269574 A2 19880601; Aduri, R., et al.: J. Chem. Theory Comput., 3, 1464 (2007);

Formula: C₁₂D₃H₁₅N₅O₄·I

Color and Shape: Neat

Molecular weight: 426.225

Ref: TR-D447412