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CAS 59867-75-3

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4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-β-D-xylofuranosyl-N-[(S)-4-amino-2-hydroxy-1-oxobutyl]-D-streptamine

Description:
The chemical substance known as "4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-β-D-xylofuranosyl-N-[(S)-4-amino-2-hydroxy-1-oxobutyl]-D-streptamine," with the CAS number 59867-75-3, is a complex glycosylated aminoglycoside antibiotic. This compound features multiple sugar moieties, including a glucopyranosyl and a xylofuranosyl unit, which contribute to its biological activity and solubility. The presence of amino groups indicates potential for hydrogen bonding and interaction with biological targets, enhancing its antimicrobial properties. The structure suggests that it may inhibit bacterial protein synthesis by binding to the ribosomal RNA, similar to other aminoglycosides. Its stereochemistry, particularly the (S)-configuration of the butyl side chain, is crucial for its biological function. This compound is of interest in medicinal chemistry for its potential therapeutic applications, particularly against resistant bacterial strains. However, detailed studies on its pharmacokinetics, toxicity, and efficacy are essential for understanding its full potential in clinical settings.
Formula:C21H41N5O13
Synonyms:
  • D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[β-D-xylofuranosyl-(1→5)]-N1-(4-amino-2-hydroxy-1-oxobutyl)-, (S)- (9CI)
  • 2-Hydroxybutirosin
  • 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-β-D-xylofuranosyl-N-[(S)-4-amino-2-hydroxy-1-oxobutyl]-D-streptamine
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