CAS 5987-73-5

6-chloro-9-(2,3,5-tri-O-acetylpentofuranosyl)-9H-purine

Description:

6-Chloro-9-(2,3,5-tri-O-acetylpentofuranosyl)-9H-purine, with the CAS number 5987-73-5, is a purine derivative characterized by the presence of a chlorine atom at the 6-position and a pentofuranosyl moiety that is fully acetylated at the 2, 3, and 5 positions. This compound exhibits properties typical of purines, including potential biological activity, as purines are fundamental components of nucleic acids and play crucial roles in cellular metabolism. The acetylation of the sugar moiety enhances its solubility and stability, which can influence its reactivity and interaction with biological targets. The chlorine substitution may also affect the compound's pharmacological properties, potentially altering its affinity for enzymes or receptors. Overall, this compound is of interest in medicinal chemistry and biochemistry, particularly in the context of nucleoside analogs and their applications in therapeutic agents or research tools.

Formula: C₁₆H₁₇ClN₄O₇

InChI: InChI=1/C16H17ClN4O7/c1-7(22)25-4-10-12(26-8(2)23)13(27-9(3)24)16(28-10)21-6-20-11-14(17)18-5-19-15(11)21/h5-6,10,12-13,16H,4H2,1-3H3

SMILES: CC(=O)OCC1C(C(C(n2cnc3c(Cl)ncnc23)O1)OC(=O)C)OC(=O)C

(2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-chloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate

CAS: 5987-73-5

Formula: C₁₆H₁₇ClN₄O₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 412.7818

Ref: IN-DA00EBG8

9-(2'',3'',5''-Tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine

CAS: 5987-73-5

Ref: 7W-GN8034

6-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

CAS: 5987-73-5

6-Chloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

Purity: 95%

Ref: 54-OR1038936

Adenosine Impurity 17

CAS: 5987-73-5

Formula: C₁₆H₁₇ClN₄O₇

Molecular weight: 412.78

Ref: 4Z-A-267033

9-(2',3',5'-Tri-O-acetyl-β-D-ribofuranosyl)-6-chloropurine

CAS: 5987-73-5

9-(2',3',5'-Tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine is an anticancer drug that belongs to the class of nucleosides. It is a modified nucleoside with a 2'-deoxyribose sugar and a 6-chloropurine base. The synthesis of 9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine can be achieved by phosphoramidite chemistry. Modified nucleosides have been found to have high antiviral and antitumour activities, as well as being promising for the treatment of HIV infections. 9-(2',3',5'-tri-O acetyl b D ribofuranosyl)-6 chloropurine has also been shown to inhibit the replication of RNA in cells infected with HIV, although it has not yet been used in humans.

Formula: C₁₆H₁₇ClN₄O₇

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 412.78 g/mol

Ref: 3D-NT10156

2,3,5-Tri-O-acetyl-6-chloropurine-9-β-D-ribofuranoside (~90%)

Controlled Product

CAS: 5987-73-5

Applications 2,3,5-Tri-O-acetyl-6-chloropurine-9-β-D-ribofuranoside is a nucleoside compound with inhibitory activity on a rho-GTPase cell protein.
References Mounetou., et al.: J. Med. Chem., 40, 2902 (1997), Panero, J., et al.: Biotech. Lett., 28, 1077 (2006),

Formula: C₁₆H₁₇ClN₄O₇

Purity: >90%

Color and Shape: Neat

Molecular weight: 412.78

Ref: TR-T736250

Adenosine Impurity 17

CAS: 5987-73-5

Formula: C₁₆H₁₇ClN₄O₇

Molecular weight: 412.78

Ref: ST-EA-CP-A88027