CAS 59870-43-8

2-chloroquinazolin-4-amine

Description:

2-Chloroquinazolin-4-amine is an organic compound characterized by its quinazoline core, which is a bicyclic structure containing both benzene and pyrimidine rings. This compound features a chlorine atom at the second position and an amino group at the fourth position of the quinazoline ring, contributing to its reactivity and potential biological activity. It is typically a white to off-white solid and is soluble in polar organic solvents. The presence of the amino group allows for hydrogen bonding, which can enhance its interactions in biological systems. 2-Chloroquinazolin-4-amine is of interest in medicinal chemistry due to its potential as a scaffold for developing pharmaceuticals, particularly in the context of targeting specific enzymes or receptors. Its chemical properties, such as melting point, boiling point, and reactivity, can vary based on the conditions and the presence of other functional groups. As with many chemical substances, safety precautions should be taken when handling it, as it may pose health risks if ingested or inhaled.

Formula: C₈H₆ClN₃

InChI: InChI=1/C8H6ClN3/c9-8-11-6-4-2-1-3-5(6)7(10)12-8/h1-4H,(H2,10,11,12)

SMILES: c1ccc2c(c1)c(=N)[nH]c(Cl)n2

Synonyms:

• 4-Quinazolinamine, 2-Chloro-
• 2-Chloroquinazolin-4-amine
• IFLAB-BB F2108-0111
• Nsc75185
• 4-Amino-2-chloroquinazoline
• 2-chloro-4-Quinazolinamine
• 2-Chloro-4-aminoquinazoline
• 2-Chloroquinazolin-4-ylamine

4-​Quinazolinamine, 2-​chloro-

CAS: 59870-43-8

Formula: C₈H₆ClN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 179.6063

Ref: IN-DA00EFGQ

4-Amino-2-chloroquinazoline

CAS: 59870-43-8

4-Amino-2-chloroquinazoline

Purity: 99%

Molecular weight: 179.61g/mol

Ref: 54-OR96169

2-Chloroquinazolin-4-amine

CAS: 59870-43-8

Formula: C₈H₆ClN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 179.61

Ref: 10-F233246

2-chloroquinazolin-4-amine

CAS: 59870-43-8

2-Chloroquinazolin-4-amine (CQA) is an anti-oxidant that exhibits significant cytotoxicity against human cancer cells. It is a competitive inhibitor of the enzyme chloride channel protein, which is involved in regulating the concentration of chloride ions in the blood. CQA has been shown to inhibit chemotaxis of white blood cells and platelets, and to have a protective effect on muscle tissue. The cytotoxic effects of CQA were shown to be due to its ability to induce apoptosis, or programmed cell death.

Formula: C₈H₆ClN₃

Purity: Min. 95%

Molecular weight: 179.6 g/mol

Ref: 3D-JCA87043