CAS 599-04-2

D-Pantolactone

Description:

D-Pantolactone, with the CAS number 599-04-2, is a cyclic ester and a derivative of pantothenic acid (vitamin B5). It is a colorless to pale yellow liquid with a slightly sweet odor and is hygroscopic in nature. D-Pantolactone is known for its role in the synthesis of various pharmaceuticals and cosmetic products due to its moisturizing properties. It has a molecular formula of C6H10O2 and a molecular weight of approximately 114.14 g/mol. The compound is soluble in water, alcohol, and other organic solvents, making it versatile for various applications. D-Pantolactone can undergo hydrolysis to form D-pantothenic acid, which is essential for the synthesis of coenzyme A in biological systems. Its stability and reactivity under different conditions make it an important intermediate in organic synthesis. Additionally, it is generally regarded as safe for use in food and cosmetic applications, although appropriate handling and safety measures should be observed due to its chemical nature.

Formula: C₆H₁₀O₃

InChI: InChI=1/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3

InChI key: InChIKey=SERHXTVXHNVDKA-BYPYZUCNSA-N

SMILES: O[C@@H]1C(C)(C)COC1=O

Synonyms:

• (-)-(R)-Pantolactone
• (-)-2-Hydroxy-3,3-dimethyl-γ-butyrolactone
• (-)-Pantoyl lactone
• (3R)-3-Hydroxy-4,4-dimethyloxolan-2-one
• (3R)-Dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone
• (3R)-Tetrahydro-3-hydroxy-4,4-dimethylfuran-2-one
• (R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one
• (R)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone
• 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (3R)-
• 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (R)-
• 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, <span class="text-smallcaps">D</span>-(-)-
• <span class="text-smallcaps">D</span>-(-)-Pantolactone
• <span class="text-smallcaps">D</span>-(-)-Pantoyl lactone
• <span class="text-smallcaps">D</span>-(-)-α-Hydroxy-β,β-dimethyl-γ-butyrolactone
• Pantolactone
• Pantothenic lactone
• l-Pantoyl lactone
• D-(-)-Pantolactone
• D-Pantolactone
• 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, D-(-)-
• R(-)-3,3-DIMETHYL-2-HYDROXY-GAMMA-BUTYROLACTONE
• ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
• D-PANTOYL LACTONE
• D-(-)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
• D-PANTOIC ACID G-LACTONE
• D-(-)-2-HYDROXY-3,3-DIMETHYL-GAMMA-BUTYROLACTONE
• D-(-)-PANTOYL LACTONE
• PANTOLACTONE-D
• 2,4-DIHYDROXY-3,3-DIMETHYLBUTYRIC ACID GAMMA-LACTONE
• PANTOIC ACID GAMMA-LACTONE
• (R)-(-)-DIHYDRO-3-HYDROXY-4,4-DIMETHYL-2(3H)-FURANONE
• (R)-(-)-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
• R(-)-2-HYDROXY-3,3-DIMETHYL-GAMMA-BUTYROLACTONE
• D-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMMA-BUTYROLACTONE
• (R)-(-)-BETA,BETA-DIMETHYL-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE

D-(-)-Pantolactone, 99%

CAS: 599-04-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₁₀O₃

Purity: 99%

Color and Shape: White, Crystalline powder or crystals

Molecular weight: 130.14

Ref: 02-L15983

PANTOLACTONE CRS

CAS: 599-04-2

PANTOLACTONE CRS

Ref: 41-Y0002109

Pantolactone

CAS: 599-04-2

Lactones, nesoi

Formula: C₆H₁₀O₃

Color and Shape: White Yellow Powder

Molecular weight: 130.06299

Ref: 45-1494807

D-(-)-Pantolactone

CAS: 599-04-2

Formula: C₆H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 130.1418

Ref: IN-DA0034OG

D-(-)-Pantolactone

CAS: 599-04-2

Formula: C₆H₁₀O₃

Purity: 99.0 - 101.0 %

Color and Shape: Colourless crystals or white crystalline powder

Molecular weight: 130.14

Ref: 7W-GX9487

D-Pantolactone

CAS: 599-04-2

D-Pantolactone

Formula: C₆H₁₀O₃

Purity: 98%

Color and Shape: white solid

Molecular weight: 130.14g/mol

Ref: 54-OR54449

(3R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one (Pantolactone)

CAS: 599-04-2

Color and Shape: Neat

Ref: 86-MM1352.03

Pantolactone

CAS: 599-04-2

Formula: C₆H₁₀O₃

Purity: 95%~99%

Molecular weight: 130.143

Ref: BP-BP4324

(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

CAS: 599-04-2

Pantolactone belongs to the class of organic compounds known as gamma-butyrolactones. gamma-Butyrolactones are compounds containing a gamma-butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and

Formula: C₆H₁₀O₃

Purity: 99.41%

Color and Shape: White Crystalline Powder Or Crystals

Molecular weight: 130.14

Ref: TM-T4828

D-(-)-Pantolactone (Dexpanthenol EP Impurity C)

CAS: 599-04-2

Formula: C₆H₁₀O₃

Molecular weight: 130.14

Ref: 4Z-B-086021

D-(-)-Pantolactone

Controlled Product

CAS: 599-04-2

Applications An important intermediate in the synthesis of pantothenic acid as well as a degradation product of pantothneic acid in the liver. Causes disorientation and hypothermia, and prevents phenamine-induced hyperthermia.
References Williams, M.: Science, 91, 246 (1940); Glaser et al.: Monatsch. Chem., 25, 46 (1904); Stiller et al.: J. Am. Chem. Soc., 62, 1785 (1940); Dorofeev, B.F. et al.: Dep. Doc., 14 (1979);

Formula: C₆H₁₀O₃

Color and Shape: Neat

Molecular weight: 130.14

Ref: TR-P182500

D-Pantolactone

CAS: 599-04-2

D-Pantolactone is a lactone that is produced by the bacterial strain Pantoea agglomerans. It is an intermediate in the biosynthesis of pantothenic acid and calcium pantothenate. D-Pantolactone has been shown to have inhibitory properties against HIV infection, but it is not active against other viruses. D-Pantolactone binds to the enzyme hydrolase and blocks the transfer of a proton from ATP to ADP, inhibiting the production of ATP and leading to cell death. The reaction solution for D-pantolactone can be analyzed using nuclear magnetic resonance spectroscopy (NMR) or high performance liquid chromatography (HPLC).

Formula: C₆H₁₀O₃

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 130.14 g/mol

Ref: 3D-FP00106

(R)-3-Hydroxy-4,4-dimethyldihydrofuran-2(3H)-one

CAS: 599-04-2

Formula: C₆H₁₀O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 130.143

Ref: 10-F337172

D-(-)-Pantolactone

CAS: 599-04-2

D-(-)-Pantolactone is a chiral compound, specifically an intermediate, which plays a crucial role in the synthesis of several pharmaceutical products. It is derived from natural sources, most commonly through the resolution of pantothenic acid or from biotechnological processes involving specific microorganisms. The compound's mode of action is based on its ability to act as a precursor or building block in enantioselective synthesis, facilitating the production of optically active compounds that are essential in drug development.

Formula: C₆H₁₀O₃

Purity: Min. 98 Area-%

Molecular weight: 130.14 g/mol

Ref: 3D-Q-200921

Dexpanthenol EP Impurity C

CAS: 599-04-2

Formula: C₆H₁₀O₃

Molecular weight: 130.10

Ref: ST-EA-CP-D106003