CAS 599-79-1

Sulfasalazine

Description:

Sulfasalazine is a medication primarily used in the treatment of inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease, as well as rheumatoid arthritis. It is a sulfonamide compound that consists of a 5-aminosalicylic acid (5-ASA) moiety linked to sulfapyridine via an azo bond. This structure allows it to exert anti-inflammatory effects in the intestines while minimizing systemic absorption. Sulfasalazine is typically administered orally and is known for its ability to reduce inflammation by inhibiting the production of pro-inflammatory cytokines and leukotrienes. The drug is generally well-tolerated, though it can cause side effects such as gastrointestinal disturbances, headache, and hypersensitivity reactions. Monitoring for potential adverse effects, including liver function and blood counts, is recommended during treatment. Additionally, sulfasalazine may interact with other medications, necessitating careful management in patients receiving multiple therapies. Overall, it plays a significant role in managing chronic inflammatory conditions, contributing to improved quality of life for many patients.

Formula: C₁₈H₁₄N₄O₅S

InChI: InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,23H,(H,19,22)(H,24,25)

InChI key: InChIKey=NCEXYHBECQHGNR-UHFFFAOYSA-N

SMILES: S(NC1=CC=CC=N1)(=O)(=O)C2=CC=C(N=NC3=CC(C(O)=O)=C(O)C=C3)C=C2

Synonyms:

• (3Z)-6-oxo-3-{[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazono}cyclohexa-1,4-diene-1-carboxylic acid
• 2-Hydroxy-5-((4-(N-(pyridin-2-yl)sulfamoyl)phenyl)diazenyl)benzoic acid
• 2-Hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]benzoic acid
• 2-Hydroxy-5-[[4-[(2-Pyridinylamino)Sulfonyl]Phenyl]Azo]Benzoic Acid
• 2-Hydroxy-5-{[4-(Pyridin-2-Ylsulfamoyl)Phenyl]Diazenyl}Benzoic Acid
• 2-hydroxy-5-{(E)-[4-(pyridin-2-ylsulfamoyl)phenyl]diazenyl}benzoic acid
• 5-(P-(2-Pyridylsulfamoyl)Phenylazo)Salicylic Acid
• 5-[4-(2-Pyridylsulfamyl)phenylazo]-2-hydroxybenzoic acid
• 5-[p-(2-Pyridylsulfamyl)phenylazo]salicylic acid
• 6-Oxo-3-{[4-(Pyridin-2-Ylsulfamoyl)Phenyl]Hydrazono}Cyclohexa-1,4-Diene-1-Carboxylic Acid
• Azopyrin
• Azopyrine
• Azulfidine
• Azulfidine EN
• Azulfin
• Benzoic acid, 2-hydroxy-5-[2-[4-[(2-pyridinylamino)sulfonyl]phenyl]diazenyl]-
• Benzoic acid, 2-hydroxy-5-[[4-[(2-pyridinylamino)sulfonyl]phenyl]azo]-
• Benzosulfa
• Colo-Pleon
• Nsc 203730
• Nsc 667219
• Reupirin
• Salazopyridin
• Salazopyrin
• Salazopyrine
• Salazosulfapiridina
• Salazosulfapyridin
• Salicylazosulfapyridine
• Salicylic acid, 5-[[p-(2-pyridylsulfamoyl)phenyl]azo]-
• Salisulf
• Sulazine
• Sulfasalazin
• Sulfasalazine

Sulfasalazine

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Purity: >95.0%(T)(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 398.39

Ref: 3B-S0580

SULFASALAZINE RS

CAS: 599-79-1

SULFASALAZINE RS

Formula: C₁₈H₁₄N₄O₅S

Molecular weight: 398.3926

Ref: 41-ICRS0424

Sulfasalazine

CAS: 599-79-1

Sulfasalazine

Formula: C₁₈H₁₄N₄O₅S

Purity: 99.6%

Color and Shape: Yellow To Dark Orange

Molecular weight: 398.06849

Ref: 47-779

SULFASALAZINE CRS

CAS: 599-79-1

SULFASALAZINE CRS

Ref: 41-S2155000

Sulfasalazine

CAS: 599-79-1

Sulfonamides used as drugs

Formula: C₁₈H₁₄N₄O₅S

Color and Shape: Brown Yellow Powder

Molecular weight: 398.06849

Ref: 45-1636005

SULFASALAZINE

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.3926

Ref: IN-DA003U6O

Sulfasalazine

CAS: 599-79-1

Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.

Formula: C₁₈H₁₄N₄O₅S

Purity: 98.00% - 99.28%

Color and Shape: Minute Brownish-Yellow Crystals

Molecular weight: 398.39

Ref: TM-T0907

2-Hydroxy-5-((4-(N-(Pyridin-2-Yl)Sulfamoyl)Phenyl)Diazenyl)Benzoic Acid

CAS: 599-79-1

2-Hydroxy-5-((4-(N-(Pyridin-2-Yl)Sulfamoyl)Phenyl)Diazenyl)Benzoic Acid

Purity: 98%

Molecular weight: 398.39g/mol

Ref: 54-OR1010474

Sulfasalazine

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Molecular weight: 398.39

Ref: 4Z-S-331

Sulfasalazine

CAS: 599-79-1

Sulfasalazine

Purity: ≥98%

Molecular weight: 398.39g/mol

Ref: 54-BUP18424

Sulfasalazine

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Purity: ≥ 98.0%

Color and Shape: Yellow to brown crystalline powder

Molecular weight: 398.39

Ref: 7W-GA4287

Sulfasalazine, USP grade

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Purity: (dried basis) 97.0 - 101.5 %

Color and Shape: Yellow to brown crystalline powder

Molecular weight: 398.39

Ref: 7W-GP4194

2-hydroxy-5-(2-{4-[(pyridin-2-yl)sulfamoyl]phenyl}diazen-1-yl)benzoic acid

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 398.39

Ref: 10-F358095

Sulfasalazine

Controlled Product

CAS: 599-79-1

Formula: C₁₈H₁₄N₄O₅S

Color and Shape: Neat

Molecular weight: 398.39

Ref: 04-C17000150

Sulfasalazine-d3

CAS: 599-79-1

Formula: C₁₈H₁₁N₄O₅SD₃

Molecular weight: 401.42

Ref: 4Z-S-332

Sulfasalazine

Controlled Product

CAS: 599-79-1

Applications Sulfasalazine is an anti-inflammatory (gastrointestinal). Sulfasalazine has been used in granulomatous colitis.
References Schroder, H., et al.: Clin. Pharmacol. Ther.,13, 539 (1972), McDonnell, J.P., et al.: Anal. Profiles Drug Subs., 5, 515 (1976), Klotz, U., et al.: Clin. Pharmacokinet.,10, 285 (1985),

Formula: C₁₈H₁₄N₄O₅S

Color and Shape: Yellow To Dark Orange

Molecular weight: 398.39

Ref: TR-S699084

Sulfasalazine

CAS: 599-79-1

Sulfasalazine is a disease-modifying anti-rheumatic drug (DMARD) with action on reducing inflammation and immune system activity and is used for treating rheumatoid arthritis and inflammatory bowel disease.

Formula: C₁₈H₁₄N₄O₅S

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 398.39 g/mol

Ref: 3D-AS27942

SULFASALAZINE

CAS: 599-79-1

Purity: 98%

Molecular weight: 398.3900146

Ref: 10-F806146