CAS 599179-03-0

5-({4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}carbonyl)-4,6-dimethylpyrimidine (2Z)-but-2-enedioate

Description:

The chemical substance known as "5-({4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}carbonyl)-4,6-dimethylpyrimidine (2Z)-but-2-enedioate" with CAS number 599179-03-0 is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups and chiral centers. This compound features a pyrimidine core, which is substituted with various piperidine and piperazine moieties, contributing to its potential biological activity. The presence of a methoxy group and a trifluoromethyl group indicates possible lipophilicity and enhanced pharmacological properties. The (2Z)-but-2-enedioate moiety suggests that it may participate in specific chemical reactions or interactions, particularly in biological systems. Overall, this compound is likely to exhibit significant interest in medicinal chemistry, particularly in the development of pharmaceuticals, due to its structural complexity and potential therapeutic applications. However, detailed studies would be necessary to fully elucidate its properties, including solubility, stability, and biological activity.

Formula: C₃₂H₄₂F₃N₅O₆

InChI: InChI=1/C28H38F3N5O2.C4H4O4/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8-23(9-7-22)28(29,30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3;5-3(6)1-2-4(7)8/h6-9,18-19,24H,10-17H2,1-5H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t19-,24-;/m0./s1

SMILES: C[C@H]1CN(CCN1[C@@H](COC)c1ccc(cc1)C(F)(F)F)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C.C(=C\C(=O)O)\C(=O)O

Synonyms:

• (4,6-Dimethylpyrimidin-5-yl){4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}methanone (2Z)-but-2-enedioate (1:1)
• methanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]-, (2Z)-2-butenedioate (1:1)
• Vicriviroc maleate
• 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate

Vicriviroc Maleate

CAS: 599179-03-0

Formula: C₃₂H₄₂F₃N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 649.7010

Ref: IN-DA00E9C8

Vicriviroc maleate

CAS: 599179-03-0

Vicriviroc maleate

Purity: ≥95%

Molecular weight: 649.7g/mol

Ref: 54-BUP07393

Vicriviroc maleate

CAS: 599179-03-0

Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.

Formula: C₃₂H₄₂F₃N₅O₆

Purity: 98.16% - 98.37%

Color and Shape: Solid

Molecular weight: 649.7

Ref: TM-T3435

Vicriviroc maleate

CAS: 599179-03-0

Vicriviroc maleate is an antiviral compound that exhibits potent activity against HIV-1. It acts by blocking the interaction between the viral envelope protein gp120 and the chemokine receptor CCR5, thereby inhibiting viral entry into target cells. Vicriviroc maleate has been shown to have high specificity for CCR5 and does not affect other chemokine receptors, such as CXCR4. This compound is available in the form of microcapsules, which provide sustained release of the active ingredient over time. The microcapsules are formulated with caffeine, phenol and/or tartaric acid, peptidoglycan, fatty acid, sevelamer, potassium borate, dopamine, and other excipients to enhance stability and bioavailability. Vicriviroc maleate is water-soluble and can be easily administered orally or intravenously. It has also been studied for its potential effects on potassium channels and chemokine-mediated signaling pathways

Formula: C₂₈H₃₈F₃N₅O₂•C₄H₄O₄

Purity: Min. 95%

Molecular weight: 649.7 g/mol

Ref: 3D-ZYA17903