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CAS 599183-35-4

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1H-Indazole-5-sulfonylchloride

Description:
1H-Indazole-5-sulfonyl chloride is a chemical compound characterized by its indazole core, which is a bicyclic structure containing a five-membered ring fused to a six-membered ring. The presence of a sulfonyl chloride group at the 5-position of the indazole ring enhances its reactivity, making it useful in various synthetic applications, particularly in the formation of sulfonamide derivatives. This compound is typically a solid at room temperature and is known for its ability to undergo nucleophilic substitution reactions, where the sulfonyl chloride can react with amines or alcohols to form sulfonamides or sulfonate esters, respectively. It is important to handle this compound with care, as sulfonyl chlorides can be corrosive and may release toxic gases upon hydrolysis. Additionally, 1H-Indazole-5-sulfonyl chloride is often utilized in medicinal chemistry and drug development due to its potential biological activity and ability to serve as a building block for more complex molecules. Proper storage and handling in a controlled environment are essential to maintain its stability and reactivity.
Formula:C7H5ClN2O2S
Synonyms:
  • 1H-Indazole-5-sulfonyl chloride
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