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CAS 59985-21-6

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Diquafosol

Description:
Diquafosol is a synthetic compound primarily used in ophthalmology, particularly for the treatment of dry eye disease. It is classified as a purinergic receptor agonist, specifically targeting the P2Y2 receptor, which plays a crucial role in promoting tear production and enhancing mucin secretion in the ocular surface. Diquafosol is typically formulated as a sterile eye drop solution, allowing for direct application to the eye. Its mechanism of action involves stimulating the natural processes of the eye to improve moisture retention and alleviate symptoms associated with dryness. The compound is known for its favorable safety profile, with minimal systemic absorption when administered topically. Diquafosol's efficacy in increasing tear film stability and reducing ocular discomfort has made it a valuable option in managing dry eye conditions. Additionally, it is important to note that, like any pharmaceutical agent, it may have potential side effects, which should be discussed with a healthcare professional.
Formula:C18H26N4O23P4
InChI:InChI=1S/C18H26N4O23P4/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30)/t7-,8-,11-,12-,13-,14-,15-,16-/m1/s1
InChI key:InChIKey=NMLMACJWHPHKGR-NCOIDOBVSA-N
SMILES:O[C@H]1[C@@H](O[C@H](COP(OP(OP(OP(OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C(=O)NC(=O)C=C3)(=O)O)(=O)O)(=O)O)(=O)O)[C@H]1O)N4C(=O)NC(=O)C=C4
Synonyms:
  • Uridine 5′-(pentahydrogen tetraphosphate), P′′′→5′-ester with uridine
  • Diquafosol
  • P1,P4-Diuridine 5′-tetraphosphate
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Found 3 products.
  • Diquafosol
    Indagoo
    + Info

    Diquafosol

    CAS:
    Formula:C18H26N4O23P4
    Molecular weight:790.3071

    Ref: IN-DA0039I5

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  • Diquafosol Free Base
    Targetmol
    + Info

    Diquafosol Free Base

    CAS:
    <p>Diquafosol Free Base is a purinoceptor P2Y(2) receptor agonist.</p>
    Formula:C18H26N4O23P4
    Color and Shape:Solid
    Molecular weight:790.31

    Ref: TM-T69030

  • Diquafosol Sodium (90%)
    TRC
    + Info

    Diquafosol Sodium (90%)

    Controlled Product
    CAS:
    <p>Stability Hygroscopic<br>Applications Diquafosol Sodium Salt, is a dinucleoside derivative of uridine that acts as a selective P2Y2 receptor agonist. Diquafosol is used as a therapeutic agent in the treatment of dry eye syndrome.<br>References Peral, A. et al.: Drugs News Pers., 2, 166 (2008); Vallejo, C.G. et al.: Biochim. Biophys. Acta Enzymol., 438, 304 (1976);<br></p>
    Formula:C18H26N4O23P4•x(Na)
    Purity:90%
    Color and Shape:Neat
    Molecular weight:790.31 • x(22.99)

    Ref: TR-D492880

    5mg
    353.00€
    50mg
    2,397.00€