CAS 60-27-5

Creatinine

Description:

Creatinine is a nitrogenous organic compound with the chemical formula C4H7N3O, primarily produced from muscle metabolism. It is a byproduct of creatine phosphate, which plays a crucial role in energy production in muscle cells. Creatinine is typically found in blood and urine, and its levels are commonly used as an indicator of kidney function. The substance is a white, crystalline powder that is soluble in water and has a slightly alkaline pH. Its molecular weight is approximately 113.12 g/mol. Creatinine is stable under normal conditions but can undergo degradation under extreme pH or temperature. In clinical settings, measuring creatinine levels helps assess renal health, as elevated levels may indicate impaired kidney function or other medical conditions. Additionally, creatinine clearance tests are often performed to evaluate glomerular filtration rate (GFR), providing insight into kidney performance. Overall, creatinine serves as an important biomarker in both clinical and physiological studies.

Formula: C₄H₇N₃O

InChI: InChI=1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

InChI key: InChIKey=DDRJAANPRJIHGJ-UHFFFAOYSA-N

SMILES: NC=1N(C)CC(=O)N1

Synonyms:

• 1-Methylglycocyamidine
• 1-Methylhydantoin-2-imide
• 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one
• 2-Amino-1-methyl-1,5-dihydroimidazol-4-one
• 2-Amino-1-methyl-4,5-dihydro-1H-imidazol-4-one
• 2-Amino-1-methylimidazolidin-4-one
• 2-Amino-1-methylimidazolin-4-one
• 2-Imino-1-Methylimidazolidine-4-One
• 2-Imino-1-Metilimidazolidin-4-Ona
• 2-Imino-1-methyl-imidazolidin-4-one
• 2-Imino-1-methylimidazolidin-4-on
• 2-Imino-1-methylimidazolidin-4-one
• 2-amino-1-methyl-1,5-dihydro-4H-imidazol-4-one
• 2-amino-3-methyl-5-oxo-4,5-dihydro-1H-imidazol-3-ium
• 4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-
• Kreatinine
• Nsc 13123
• TEGO Cosmo C 250

Creatinine - tests performed to USP

CAS: 60-27-5

Creatinine is the end product of creatine, which is a natural substance found in muscle tissue. Creatinine levels are used to measure how well the kidneys are functioning. Creatinine is also a component of total protein and blood urea nitrogen (BUN). Creatinine has been shown to have a positive effect on HIV-infected patients by stimulating the production of colony-stimulating factor, which helps to build up the immune system. Creatinine can be detected in blood samples using an enzyme activity assay or it can be measured using creatinine assays that use skin cells or biological samples. Creatinine levels are also used to diagnose conditions such as kidney dysfunction, liver disease, and heart failure. Creatinine levels may also be used to help predict prognosis for untreated group p2 with glomerular filtration rate (GFR) less than 60ml/min per 1.73m2 body surface area.

Formula: C₄H₇N₃O

Color and Shape: Powder

Molecular weight: 113.12 g/mol

Ref: 3D-FC178344