CAS 60-70-8
:Veratramine
Description:
Veratramine is an alkaloid derived from the plant genus Veratrum, commonly known as false hellebore. It is characterized by its complex molecular structure, which includes multiple rings and functional groups, contributing to its biological activity. Veratramine is known for its pharmacological properties, particularly its ability to act as a vasodilator and its potential effects on the cardiovascular system. It has been studied for its role in modulating blood pressure and its influence on neurotransmitter systems. The substance is typically found in a crystalline form and is soluble in organic solvents, but its solubility in water is limited. Due to its biological activity, veratramine has been of interest in medicinal chemistry, although its use is often restricted due to potential toxicity and side effects. Safety precautions are necessary when handling this compound, as it can exhibit significant physiological effects. Overall, veratramine represents a fascinating example of natural products with potential therapeutic applications, warranting further research into its mechanisms and effects.
Formula:C27H39NO2
InChI:InChI=1S/C27H39NO2/c1-15-11-25(30)26(28-14-15)17(3)20-7-8-21-22-6-5-18-12-19(29)9-10-27(18,4)24(22)13-23(21)16(20)2/h5,7-8,15,17,19,22,24-26,28-30H,6,9-14H2,1-4H3/t15-,17-,19-,22-,24-,25+,26-,27-/m0/s1
InChI key:InChIKey=MALFODICFSIXPO-KFKQDBFTSA-N
SMILES:C[C@@]12[C@@]3([C@](C=4C(C3)=C(C)C([C@H](C)[C@]5([C@H](O)C[C@H](C)CN5)[H])=CC4)(CC=C1C[C@@H](O)CC2)[H])[H]
Synonyms:- (2S,3R,5S)-5-Methyl-2-[(1S)-1-[(3S,6aR,11aS,11bR)-2,3,4,6,6a,11,11a,11b-octahydro-3-hydroxy-10,11b-dimethyl-1H-benzo[a]fluoren-9-yl]ethyl]-3-piperidinol
- (3beta,23R)-14,15,16,17-tetradehydroveratraman-3,23-diol
- (3beta,23beta)-14,15,16,17-Tetradehydroveratraman-3,23-diol
- 14,15,16,17-Tetradehydroveratraman-3,23-Diol
- 1H-Benzo[a]fluorene, veratraman-3,23-diol deriv.
- 3-Piperidinol, 5-methyl-2-[(1S)-1-[(3S,6aR,11aS,11bR)-2,3,4,6,6a,11,11a,11b-octahydro-3-hydroxy-10,11b-dimethyl-1H-benzo[a]fluoren-9-yl]ethyl]-, (2S,3R,5S)-
- Brn 0055515
- Hsdb 3545
- Nsc 17821
- Nsc 23880
- Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3-beta,23-beta)-
- Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3beta,23beta)- (9CI)
- Veratraman-3,23-diol, 14,15,16,17-tetradehydro-, (3β,23β)-
- Veratramine
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Found 13 products.
Veratramine
CAS:<p>Veratramine (NSC-23880)(NSC-17821; NSC-23880) is a potent signal transduction inhibitor for treating tumors.</p>Formula:C27H39NO2Purity:99.7% - 99.75%Color and Shape:SolidMolecular weight:409.6Veratramine
CAS:Natural alkaloidFormula:C27H39NO2Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:409.61Veratramine
CAS:Controlled Product<p>Applications Veratramine is useful as signal transduction inhibitor for treating tumors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Imamura, L., et al.: J. Trad. Med., 12, 129 (1995), Ingolfsdottir, K., et al.: Antimicrob. Agents. Chemother., 1997, 41, 215 (1997), Tezuka, Y., et al.: J. Nat. Prod., 61, 1397 (1988)<br></p>Formula:C27H39NO2Color and Shape:WhiteMolecular weight:409.60Veratramine
CAS:<p>Veratramine is a natural drug that is used as an anti-inflammatory agent and for the treatment of autoimmune diseases. It has been shown to have significant cytotoxicity in epithelial cells, but not in mesenchymal cells. Veratramine also has a matrix effect on these cell types. Veratramine's surface methodology can be used to measure the degree of inflammation by measuring the level of cytokines at the site of injury. This technique also allows for analysis of human serum samples using LC-MS/MS techniques to identify acute toxicities and steroid alkaloids that may be present.</p>Formula:C27H39NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:409.60 g/molVeratramine
CAS:Formula:C27H39NO2Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:409.61
