CAS 60-80-0

Antipyrine

Description:

Antipyrine, with the CAS number 60-80-0, is an organic compound belonging to the class of pyrazolones. It is characterized by its white to pale yellow crystalline appearance and is known for its analgesic, antipyretic, and anti-inflammatory properties. Antipyrine has a molecular formula of C11H12N2O and a molecular weight of approximately 188.23 g/mol. It is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water. Antipyrine acts by inhibiting the production of prostaglandins, which are mediators of pain and fever. Historically, it has been used in various medical applications, including pain relief and fever reduction, although its use has declined with the advent of newer medications. Additionally, antipyrine is sometimes employed in pharmacokinetic studies to assess liver function due to its metabolism in the liver. Safety considerations include potential side effects such as allergic reactions and hematological disturbances, necessitating careful monitoring during use.

Formula: C₁₁H₁₂N₂O

InChI: InChI: 1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChI key: InChIKey=VEQOALNAAJBPNY-UHFFFAOYSA-N

SMILES: CN1N(C(=O)C=C1C)C2=CC=CC=C2

Synonyms:

• 1,2-Dihydro-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One
• 1,5-Dimethyl-2-Phenyl-Pyrazolidin-3-One
• 1,5-Dimethyl-2-phenyl-1,2-dihydropyrazol-3-one
• 1,5-Dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
• 1,5-Dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
• 1,5-Dimethyl-2-phenylpyrazol-3-one
• 1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
• 1-Phenyl-2,3-dimethyl-5-pyrazolone
• 2,3-Dimethyl-1-phenyl-3-pyrazolin-3-one
• 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one
• 2,3-Dimethyl-1-phenyl-5-pyrazolone
• 2-Phenyl-1,5-dimethyl-3-pyrazolone
• 3H-Pyrazol-3-One, 1,2-Dihydro-1,5-Dimethyl-2- Phenyl-
• Analgesin
• Analgesine
• Anodynin
• Anodynine
• Antipirin
• Antipyrene
• Antipyrin
• Antipyrine,(2,3-Dimethyl-1-phenyl-3-pyr
• Antypirine
• Apirelina
• Apyretine
• Azophen
• Azophene
• Dentigoa N
• Dimethyloxychinizin
• Dimethyloxyquinazine
• Eu-Med mono
• Fenazona
• Fenazone
• Methozin
• Nsc 7945
• Oxydimethylquinazine
• Parodyne
• Phenazon
• Phenazone
• Phenazone (pharmaceutical)
• Phenylon
• Phenylone
• Pyrazophyl
• Sedatin
• Sedatine
• antipyrin(R)
• Antipyrine
• 1,5-DIMETHYL-2-PHENYL-3-PYRAZOLONE
• 1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
• 1,5-Dimethyl1-2-phenyl-3-pyrazolone
• 1-Phenyl-2,3-dimethylpyrazole-5-one
• PHENAZONUM
• 1,2-dihydro-1,5-dimethyl-2-phenyl-3h-pyrazol-3-on
• 1-PHENYL-2,3-DIMETHYLPYRAZOL-5-ONE
• OXYDIMETHYLQUINIZINE
• AURORA KA-3852

Antipyrine

CAS: 60-80-0

Formula: C₁₁H₁₂N₂O

Purity: >99.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 188.23

Ref: 3B-D1876

Antipyrine, 98%

CAS: 60-80-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₁₂N₂O

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 188.23

Ref: 02-A11089

Phenazone

CAS: 60-80-0

Color and Shape: Neat

Ref: 61-FOR0036.05

PHENAZONE CRS

CAS: 60-80-0

PHENAZONE CRS

Formula: C₁₁H₁₂N₂O

Color and Shape: Crystalline Powder. White. Colourless Crystals. Powder.

Molecular weight: 188.2258

Ref: 41-P0800000

Antipyrine

CAS: 60-80-0

Phenazone (antipyrine) and its derivatives

Formula: C₁₁H₁₂N₂O

Color and Shape: Powder

Molecular weight: 188.09496

Ref: 45-1040005

3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-2-phenyl-

CAS: 60-80-0

Formula: C₁₁H₁₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 188.2258

Ref: IN-DA00IAN3

Antipyrine

CAS: 60-80-0

Antipyrine, an analgesic/antipyretic, used orally or as ear drops, tests liver enzyme response to diseases/drugs.

Formula: C₁₁H₁₂N₂O

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 188.23

Ref: TM-T0734

Antipyrine

CAS: 60-80-0

Antipyrine

Purity: ≥98%

Molecular weight: 188.23g/mol

Ref: 54-BUP19594

Propyphenazone EP Impurity A (Phenazone)

CAS: 60-80-0

Formula: C₁₁H₁₂N₃O

Color and Shape: White To Off-White Solid

Molecular weight: 188.23

Ref: 4Z-P-177001

Phenazone

CAS: 60-80-0

Formula: C₁₁H₁₂N₂O

Color and Shape: Neat

Molecular weight: 188.23

Ref: 04-C16003100

Phenazone

CAS: 60-80-0

Color and Shape: Neat

Ref: 86-MM0036.05

Antipyrine

CAS: 60-80-0

Applications Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
References Gong H et al. Water Res. 2017 Apr 1;112:167-175Quintão NL et al. Anesth Analg. 2010 Mar 1;110(3):942-50Farrell GC et al. Br J Clin Pharmacol. 1984 Oct;18(4):559-65.

Formula: C₁₁H₁₂N₂O

Color and Shape: White

Molecular weight: 188.23

Ref: TR-A697500

1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one

CAS: 60-80-0

1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one (1,2DHDP) is a chemical inhibitor that prevents the activity of enzymes by binding to their active site. 1,2DHDP has been shown to inhibit the enzyme pyrazole ring synthesis in rat liver microsomes. It also inhibits the production of antimicrobial agents and has been used as a sample preparation agent. 1,2DHDP also interferes with drug interactions by inhibiting cytochrome P450 enzymes in the liver. This compound can be used for wastewater treatment because it is not toxic to bacteria or plants. The mechanism of this inhibitor is unknown but may be due to its ability to bind to the dinucleotide phosphate cofactor at the active site of an enzyme.

Formula: C₁₁H₁₂N₂O

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 188.23 g/mol

Ref: 3D-FD75059

1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one

CAS: 60-80-0

Formula: C₁₁H₁₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 188.23

Ref: 10-F358184