CAS 60-89-9

10-[(1-Methyl-3-piperidyl)methyl]phenothiazine

Description:

10-[(1-Methyl-3-piperidyl)methyl]phenothiazine, commonly known as thioridazine, is an antipsychotic medication primarily used to treat schizophrenia and other psychotic disorders. It belongs to the phenothiazine class of compounds, characterized by a three-ring structure that includes a sulfur atom. Thioridazine exhibits sedative and tranquilizing properties, which are attributed to its ability to antagonize dopamine receptors in the central nervous system. The compound is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing in many cases. Thioridazine can cause side effects, including sedation, dry mouth, and potential cardiovascular issues, particularly at higher doses. It is important to monitor patients for extrapyramidal symptoms, which are common with antipsychotic medications. Due to safety concerns, its use has declined in favor of newer antipsychotics with a more favorable side effect profile. Overall, thioridazine remains a significant compound in the history of psychiatric treatment, illustrating the evolution of antipsychotic therapy.

Formula: C₁₉H₂₂N₂S

InChI: InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3

InChI key: InChIKey=CBHCDHNUZWWAPP-UHFFFAOYSA-N

SMILES: C(N1C=2C(SC=3C1=CC=CC3)=CC=CC2)C4CN(C)CCC4

Synonyms:

• (N-Methyl-3-piperidyl)methylphenothiazine
• 10-(1-Methyl-3-Piperidylmethyl)Phenothiazine
• 10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine
• 10-[(1-Methyl-3-piperidyl)methyl]phenothiazine
• 10-[(1-Methylpiperidin-3-yl)methyl]phenothiazine
• 10-[(1-methylpiperidin-3-yl)methyl]-10H-phenothiazine
• 10H-Phenothiazine, 10-[(1-methyl-3-piperidinyl)methyl]-
• Iii 2318
• Lacumin
• Mepazin
• Mepazine
• Mepazine base
• Meprazine
• Mesapin
• Nothiazine
• P 391
• Pacatal
• Pacatal base
• Pacatol
• Pakatal
• Paxital
• Pecatal

Mepazine

CAS: 60-89-9

Mepazine

Purity: ≥98%

Molecular weight: 310.46g/mol

Ref: 54-BUP16264

Pecazine-d3

Controlled Product

CAS: 60-89-9

Formula: C₁₉H₁₉D₃N₂S

Color and Shape: Neat

Molecular weight: 313.48

Ref: TR-P218287

Pecazine

Controlled Product

CAS: 60-89-9

Pecazine is a nonsteroidal anti-inflammatory drug that is used to treat bowel disease. It inhibits the protease activity of inflammatory cells, which causes the release of inflammatory substances such as prostaglandins and leukotrienes. Pecazine also reduces the redox potential in the body, which may be due to its ability to inhibit oxidative enzyme activity. This drug has been shown to be effective in treating inflammatory bowel disease.

Formula: C₁₉H₂₂N₂S

Purity: Min. 95%

Molecular weight: 310.5 g/mol

Ref: 3D-AAA06089

Mepazine

CAS: 60-89-9

Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.

Formula: C₁₉H₂₂N₂S

Purity: 99.88% - 99.92%

Color and Shape: Solid

Molecular weight: 310.46

Ref: TM-T16040