CAS 60-93-5

(-)-Quinine dihydrochloride

Description:

(-)-Quinine dihydrochloride is a chemical compound derived from the bark of the cinchona tree, known for its historical use as an antimalarial agent. It is a stereoisomer of quinine, characterized by its specific optical activity, which is attributed to its chiral structure. The compound is a white to off-white crystalline powder that is soluble in water, making it suitable for various pharmaceutical applications. As a dihydrochloride salt, it contains two hydrochloride groups, enhancing its solubility and stability in aqueous solutions. (-)-Quinine dihydrochloride exhibits a bitter taste and has been used not only in medicine but also as a flavoring agent in tonic water. Its mechanism of action primarily involves the inhibition of heme polymerization in the malaria parasite, disrupting its ability to detoxify heme, which is toxic to the organism. Additionally, it has been studied for its potential effects on cardiac function and as an analgesic. Safety and dosage considerations are crucial, as it can have side effects and interactions with other medications.

Formula: C₂₀H₂₄N₂O₂·2ClH

InChI: InChI=1S/C20H24N2O2.2ClH/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;2*1H/t13-,14-,19-,20+;;/m0../s1

InChI key: InChIKey=NNKXWRRDHYTHFP-HZQSTTLBSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H].Cl

Synonyms:

• (8alpha,9R)-6'-methoxycinchonan-9-ol dihydrochloride
• Acid quinine hydrochloride
• Cinchonan-9-ol, 6′-methoxy-, dihydrochloride, (8α,9R)-
• Cinchonan-9-ol, 6′-methoxy-, hydrochloride (1:2), (8α,9R)-
• Quinine Dihydochloride
• Quinine bimuriate
• Quinine, dihydrochloride

Quinine Dihydrochloride

CAS: 60-93-5

Color and Shape: Neat

Ref: 61-FOR0458.00

Quinine dihydrochloride

CAS: 60-93-5

Formula: C₂₀H₂₆Cl₂N₂O₂

Purity: 98%

Molecular weight: 397.3386

Ref: IN-DA00E8VL

Quinine dihydrochloride

CAS: 60-93-5

Quinine dihydrochloride

Purity: ≥98%

Molecular weight: 397.34g/mol

Ref: 54-BUP15103

Quinine Dihydrochloride

Controlled Product

CAS: 60-93-5

Formula: C₂₀H₂₄N₂O₂ClH

Color and Shape: Neat

Molecular weight: 397.34

Ref: 86-MM0458.00

Quinine dihydrochloride

CAS: 60-93-5

Quinine dihydrochloride (Quinine bimuriate) is a primary alkaloid of various species of Cinchona (Rubiaceae).

Formula: C₂₀H₂₆Cl₂N₂O₂

Purity: 99.79% - 99.97%

Color and Shape: White Solid

Molecular weight: 397.34

Ref: TM-T4333

Quinine Dihydrochloride

CAS: 60-93-5

Formula: C₂₀H₂₄N₂O₂(HCl)

Molecular weight: 324.42 : 2(36.46)

Ref: ST-EA-CP-Q3007