CAS 60-99-1

10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-, (βR)-

Description:

The chemical substance known as "10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-, (βR)-" with CAS number 60-99-1 is a derivative of phenothiazine, a compound characterized by its tricyclic structure containing sulfur and nitrogen atoms. This specific compound features a propanamine side chain and a methoxy group, which contribute to its unique properties. It is typically recognized for its potential applications in medicinal chemistry, particularly as an antipsychotic or tranquilizing agent due to its ability to interact with neurotransmitter systems in the brain. The presence of the trimethyl group enhances its lipophilicity, which can influence its pharmacokinetic properties, such as absorption and distribution in biological systems. Additionally, the stereochemistry indicated by (βR)- suggests a specific spatial arrangement of atoms, which can significantly affect the compound's biological activity and interaction with receptors. Overall, this compound exemplifies the diverse functionalities that can arise from modifications to the phenothiazine core structure.

Formula: C₁₉H₂₄N₂OS

InChI: InChI=1/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-11-15(22-4)9-10-17(19)21/h5-11,14H,12-13H2,1-4H3

InChI key: InChIKey=VRQVVMDWGGWHTJ-CQSZACIVSA-N

SMILES: C([C@@H](CN(C)C)C)N1C=2C(SC=3C1=CC=CC3)=CC=C(OC)C2

Synonyms:

• (2R)-3-(2-Methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
• (βR)-2-Methoxy-N,N,β-trimethyl-10H-phenothiazine-10-propanamine
• 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-, (R)-
• 2-Methoxytrimeprazine
• 7044 R.P.
• Cl 36467
• Cl 39743
• Hirnamin
• L-2-Methoxy-10-(3'-dimethylamino-2'-methylpropyl)-phenothiazine
• Levomeprazine
• Levomepromazin
• Levomepromazina
• Levomepromazine
• Levopromazine
• Levoprome
• Levopromethazine
• Levotomin
• Mepromazine
• Methotrimeprazine
• Neozine
• Nirvan
• Nozinan
• Nozinane
• Nsc 226516
• Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-2-methoxy-, (-)-
• Rp 7044
• Sinogan
• Sinogan-Debil
• Skf 5116
• Tisercin
• Xp 03
• (-)-3-(2-methoxyphenothiazin-10-yl)-2-methylpropyldimethylamine
• (2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
• Levomepromazine base
• 3-(3-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
• 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-, (βR)-
• SK&F 5116
• methotrimeprazine maleate USP/EP/BP
• C07192
• milezin
• (R)-2-Methoxy-N,N,-trimethyl-10H-phenothiazine-10-propanamine
• 3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethyl-1-propanamine
• Levomepropazine
• rp7044
• 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, (R)-
• cl53212
• Veractil
• 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, (-)-
• methotrimeprazine maleate
• METHOTRIMEPRAZINE MALEATE SALT
• Methotrimeprazine (200 mg)
• Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-2-methoxy-, (-)- (8CI)
• hirnamine
• 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,b-trimethyl-, (bR)- (9CI)
• dedoran
• Neurocil
• Levoprom
• n,beta-trimethyl-2-methoxy-(r)-10h-phenothiazine-10-propanamin
• (-)-phenothiazin
• Methotrimeprazine-d3 maleate
• (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT
• levopromazioni
• minozinan
• cl39743
• (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine
• methoxytrimeprazine
• bayer1213
• nirnamine
• cl36467
• (-)-10-(3-[DIMETHYLAMINO]-2-METHYLPROPYL)-2-METHOXY-PHENOTHIAZINE MALEATE SALT USP/EP/BP
• arc-vi-c-5
• skf5116
• nomizan

Methotrimeprazine

CAS: 60-99-1

Antidepressants, tranquilizers and other pschotherapeutic agents

Formula: C₁₉H₂₄N₂OS

Color and Shape: White Crystalline Powder

Molecular weight: 328.16093

Ref: 45-1415006

Levomepromazine

CAS: 60-99-1

Formula: C₁₉H₂₄N₂OS

Color and Shape: White To Off-White Solid

Molecular weight: 328.47

Ref: 4Z-L-104001

Levomepromazine

CAS: 60-99-1

Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.

Formula: C₁₉H₂₄N₂OS

Purity: 99.15%

Color and Shape: Solid

Molecular weight: 328.47

Ref: TM-T15743

Levomepromazine-13C-d3

CAS: 60-99-1

Formula: CC₁₈H₂₁D₃N₂OS

Molecular weight: 332.48

Ref: 4Z-L-104005

Levo Mepromazine-d3

Controlled Product

CAS: 60-99-1

Applications Methotrimeprazine-d3, is the labeled analogue of Methotrimeprazine, used as an Analgesic.
References Haddad, P., et al.: Drugs, 62, 1649 (2002), Chiu, P., et al.: J. Pharmacol. Sci., 95, 311 (2004), Dubin, A., et al.: J. Biomol. Screen, 10, 168 (2005),

Formula: C₁₉H₂₁D₃N₂OS

Color and Shape: Off White Powder

Molecular weight: 331.49

Ref: TR-L375752

(R)-Methotrimeprazine

Controlled Product

CAS: 60-99-1

Formula: C₁₉H₂₄N₂OS

Color and Shape: Neat

Molecular weight: 328.47

Ref: TR-M260770

Methotrimeprazine

Controlled Product

CAS: 60-99-1

Methotrimeprazine is a drug that belongs to the group of drugs called psychotropic agents. It is used as an antipsychotic, antidepressant, and anxiolytic. Methotrimeprazine is also known as a "mood stabilizer" because it can help control mood swings in people with bipolar disorder. Methotrimeprazine has been shown to have a significant effect on the symptoms of carcinoid syndrome and infectious diseases, including HIV/AIDS. It may be effective against other autoimmune disorders such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, psoriasis, and lupus erythematosus. The mechanism of action for methotrimeprazine is not yet fully understood but it has been shown to have receptor activity on the dopamine receptors in the brain and it may act as a modulator of cannabinoid derivatives. Methotrimeprazine is available as

Formula: C₁₉H₂₄N₂OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.47 g/mol

Ref: 3D-FM165717