CAS 600-57-7

11β-Hydroxyprogesterone

Description:

11β-Hydroxyprogesterone, also known as 11β-hydroxyprogesterone or 11-OH-progesterone, is a steroid hormone that plays a crucial role in the regulation of various physiological processes. It is a derivative of progesterone, characterized by the presence of a hydroxyl group at the 11β position. This modification influences its biological activity and receptor binding affinity. The substance is typically a white to off-white crystalline powder, and it is soluble in organic solvents such as ethanol and methanol but has limited solubility in water. 11β-Hydroxyprogesterone is involved in the biosynthesis of corticosteroids and is significant in the context of adrenal function and reproductive health. It is often studied in relation to its effects on the menstrual cycle, pregnancy, and various endocrine disorders. In laboratory settings, it may be used as a reference standard in assays and research related to steroid hormones. Safety and handling precautions should be observed, as with all chemical substances, due to potential biological effects.

Formula: C₂₁H₃₀O₃

InChI: InChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18-,19+,20-,21+/m0/s1

InChI key: InChIKey=BFZHCUBIASXHPK-ATWVFEABSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@@H](C(C)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• 11β-Hydroxyprogesterone
• Pregn-4-ene-3,20-dione, 11β-hydroxy-
• Pregn-4-en-11β-ol-3,20-dione
• Pregn-4-ene-3,20-dione, 11-hydroxy-, (11β)-
• (11β)-11-Hydroxypregn-4-ene-3,20-dione

11β-Hydroxyprogesterone

CAS: 600-57-7

Formula: C₂₁H₃₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 330.4611

Ref: IN-DA00EFN2

11β-hydroxyprogesterone

CAS: 600-57-7

11β-hydroxyprogesterone

Purity: ≥98%

Molecular weight: 330.46g/mol

Ref: 54-BUP20219

11β-hydroxyprogesterone

CAS: 600-57-7

The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro

Formula: C₂₁H₃₀O₃

Purity: 99.51% - 99.52%

Color and Shape: Solid

Molecular weight: 330.46

Ref: TM-TCA2511

11β-Hydroxy Progesterone

Controlled Product

CAS: 600-57-7

Applications 11beta-Hydroxyprogesterone (CAS# 600-57-7) is a useful research chemical compound.

Formula: C₂₁H₃₀O₃

Color and Shape: White To Off-White

Molecular weight: 330.46

Ref: TR-B249680

11beta-Hydroxyprogesterone

Controlled Product

CAS: 600-57-7

11β-hydroxyprogesterone is a naturally occurring steroid hormone that is produced in the adrenal glands and the placenta. It is also a metabolite of progesterone. It has been found to have physiological levels in vitro and in cell culture experiments, where it has shown to stimulate epidermal growth factor (EGF) synthesis and inhibit protein transport. This hormone may be involved in women's reproductive cycle, as it has been found to have a stimulatory effect on the production of oestrogen by ovarian cells. 11β-hydroxyprogesterone is also used as an immunosuppressant drug (e.g., for treating rheumatoid arthritis). It inhibits the activity of bacterial enzymes such as hydroxylases and urease, which are required for bacterial growth. This drug has been found to be beneficial in treating polycystic ovarian syndrome (PCOS) because it may improve ovulation rates and decrease testosterone levels.

Formula: C₂₁H₃₀O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 330.46 g/mol

Ref: 3D-FH65893