CAS 600-90-8

Epiprednisolone

Description:

Epiprednisolone is a synthetic glucocorticoid, primarily used for its anti-inflammatory and immunosuppressive properties. It is a derivative of prednisolone, characterized by its ability to modulate various physiological processes, including the immune response and inflammation. The chemical structure of epiprednisolone features a steroid backbone, which is essential for its biological activity. It is typically administered in the form of oral tablets or injectable solutions, and its pharmacological effects are mediated through the glucocorticoid receptor, leading to alterations in gene expression. Common therapeutic applications include the treatment of conditions such as allergies, asthma, autoimmune disorders, and certain types of cancer. While effective, epiprednisolone can also have side effects, including weight gain, mood changes, and increased susceptibility to infections, particularly with prolonged use. As with other corticosteroids, careful monitoring and dosage adjustments are essential to minimize adverse effects while maximizing therapeutic benefits.

Formula: C21H28O5

InChI: InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16+,18+,19-,20-,21-/m0/s1

InChI key: OIGNJSKKLXVSLS-MKIDGPAKSA-N

SMILES: C[C@]12C[C@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O

Synonyms:

• Prednisolone EP Impurity F (11-Epi-prednisolone)
• Prednisolone EP Impurity F
• Epiprednisolone
• Prednisone impurity F (EP)
• (8S,9S,10R,11R,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one