CAS 60021-32-1

Estra-1,3,5(10)-triene-3,4,16,17-tetrol, (16α,17β)-

Description:

Estra-1,3,5(10)-triene-3,4,16,17-tetrol, also known by its CAS number 60021-32-1, is a synthetic steroid compound that belongs to the class of estrogens. This compound features a polycyclic structure characteristic of steroid hormones, with multiple hydroxyl (-OH) groups that contribute to its biological activity. The presence of these hydroxyl groups enhances its solubility in polar solvents and influences its interaction with estrogen receptors in the body. The specific stereochemistry indicated by the (16α,17β) designation suggests a particular spatial arrangement of atoms that can significantly affect the compound's pharmacological properties, including its potency and efficacy as an estrogenic agent. Estra-1,3,5(10)-triene-3,4,16,17-tetrol is primarily studied for its potential applications in hormone replacement therapy and its role in various physiological processes. As with many steroid compounds, its stability, reactivity, and biological effects are influenced by its molecular structure, making it a subject of interest in medicinal chemistry and endocrinology.

Formula: C₁₈H₂₄O₄

InChI: InChI=1S/C18H24O4/c1-18-7-6-10-9-4-5-14(19)16(21)12(9)3-2-11(10)13(18)8-15(20)17(18)22/h4-5,10-11,13,15,17,19-22H,2-3,6-8H2,1H3/t10-,11-,13+,15-,17+,18+/m1/s1

InChI key: InChIKey=KKXSCWWODCABHQ-OZPBLJIJSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=C(O)C(O)=CC4)(CC1)[H])[H])(C[C@@H](O)[C@@H]2O)[H]

Synonyms:

• 4-Hydroxyestriol
• Estra-1,3,5(10)-Triene-3,4,16,17-Tetrol, (16Alpha,17Beta)-
• Estra-1,3,5(10)-triene-3,4,16,17-tetrol, (16α,17β)-
• (16alpha,17beta)-Estra-1,3,5(10)-triene-3,4,16,17-tetrol

4-Hydroxyestriol

Controlled Product

CAS: 60021-32-1

4-Hydroxyestriol is a medicinal compound that has been shown to have anticancer properties. It is an analog of the hormone estrogen and acts as an inhibitor of cancer cell growth by blocking the activity of protein kinases. This compound has been found in human urine and may be useful in the treatment of various forms of cancer, including breast and prostate cancer. 4-Hydroxyestriol has been shown to induce apoptosis, or programmed cell death, in cancer cells. This compound may also be used in combination with other inhibitors, such as nalbuphine or Chinese medicinal inhibitors, to enhance its anticancer effects.

Formula: C₁₈H₂₄O₄

Purity: Min. 95%

Molecular weight: 304.4 g/mol

Ref: 3D-KCA02132