CAS 60070-14-6

1a,10b-Dihydrodibenzo[a,e]cyclopropa[c]cyclohepten-6(1H)-one O-(2-aminoethyl)oxime

Description:

1a,10b-Dihydrodibenzo[a,e]cyclopropa[c]cyclohepten-6(1H)-one O-(2-aminoethyl)oxime, with CAS number 60070-14-6, is a complex organic compound characterized by its unique bicyclic structure, which incorporates both cyclopropane and cycloheptene moieties. This compound features a ketone functional group and an oxime, which is derived from the reaction of the ketone with hydroxylamine. The presence of the aminoethyl group enhances its potential for biological activity, possibly influencing its solubility and reactivity. The compound's structure suggests it may exhibit interesting chemical properties, such as the ability to participate in various chemical reactions, including nucleophilic substitutions and cycloadditions. Additionally, its unique arrangement of carbon atoms and functional groups may contribute to specific interactions with biological targets, making it of interest in medicinal chemistry and drug development. However, detailed studies on its physical properties, such as melting point, boiling point, and solubility, as well as its biological activity, would be necessary to fully understand its potential applications.

Formula: C₁₈H₁₈N₂O

InChI: InChI=1/C18H18N2O/c19-9-10-21-20-18-14-7-3-1-5-12(14)16-11-17(16)13-6-2-4-8-15(13)18/h1-8,16-17H,9-11,19H2

InChI key: InChIKey=ZJUNTBVPKYZTPD-UHFFFAOYSA-N

SMILES: N(OCCN)=C1C=2C(C3C(C3)C=4C1=CC=CC4)=CC=CC2

Synonyms:

• 1a,10b-Dihydrodibenzo(a,e)cyclopropa(c)cyclohepten-6(1H)-one O-(2-aminoethyl)oxime
• 2-[(1a,10b-dihydrodibenzo[a,e]cyclopropa[c][7]annulen-6(1H)-ylideneamino)oxy]ethanamine
• Dibenzo[a,e]cyclopropa[c]cyclohepten-6(1H)-one, 1a,10b-dihydro-, O-(2-aminoethyl)oxime
• Mariptilina
• Mariptiline [INN]
• Mariptilinum
• Unii-E27T357050
• Mariptiline

Mariptiline

CAS: 60070-14-6

Mariptiline is a monoamine oxidase inhibitor that can be used to inhibit the uptake of monoamines and may be useful in the treatment of cancer. It acts as a targetable uptake inhibitor by binding to the membrane transporter responsible for transporting amines into cells. The drug is insoluble and must be reconstituted with a diluent before use. Mariptiline can also be administered by iontophoresis, which delivers drugs through electric current. This method may be more effective than oral ingestion because it circumferentially delivers drugs to tumors. Mariptiline inhibits the activity of an enzyme called foxo1, which is involved in tumor development and progression, making it a possible therapeutic agent for treating cancer. Mariptiline also has been shown to inhibit α2-adrenergic receptors, which are implicated in the regulation of tumor growth and metastasis.

Formula: C₁₈H₁₈N₂O

Purity: Min. 95%

Molecular weight: 278.35 g/mol

Ref: 3D-FM170108