CAS 6009-98-9

taurochenodeoxycholic acid sodium salt

Description:

Taurochenodeoxycholic acid sodium salt is a bile acid derivative that plays a significant role in the digestion and absorption of fats and fat-soluble vitamins in the intestine. It is a sodium salt of taurochenodeoxycholic acid, which is formed by the conjugation of chenodeoxycholic acid with taurine. This compound is typically found in the bile of mammals and is involved in the emulsification of dietary lipids. Characteristically, it is a white to off-white powder that is soluble in water, reflecting its ionic nature due to the presence of the sodium ion. The substance exhibits amphipathic properties, allowing it to interact with both hydrophilic and hydrophobic environments, which is crucial for its function in lipid metabolism. Additionally, taurochenodeoxycholic acid sodium salt has been studied for its potential therapeutic applications, including its effects on cholesterol metabolism and its role in various gastrointestinal disorders. Its safety profile and biological activity make it a subject of interest in both clinical and pharmaceutical research.

Formula: C₂₆H₄₄NNaO₆S

InChI: InChI=1/C26H45NO6S.Na/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29;/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/t16-,17+,18-,19-,20+,21+,22-,24+,25+,26-;/m1./s1

Synonyms:

• Sodium taurochenodeoxycholate
• Sodium 2-[(3,7-Dihydroxy-24-Oxocholan-24-Yl)Amino]Ethanesulfonate
• Ethanesulfonic Acid, 2-[[(3Alpha,5Beta,7Alpha)-3,7-Dihydroxy-24-Oxocholan-24-Yl]Amino]-, Monosodium Salt
• Taurochenodeoxycholic Acid, Sodium Salt
• 2-[(3ALPHA,7ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)AMINO]ETHANESULFONIC ACID SODIUM SALT
• 5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE-3ALPHA,7ALPHA-DIOL SODIUM SALT
• SODIUM TAUROCHENODEOXYCHOLIC ACID
• 3ALPHA,7ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
• TAUROCHENODESOXYCHOLIC ACID, SODIUM SALT
• 2-([3-ALPHA,7-ALPHA-DIHYDROXY-24-OXO-5-BETA-CHOLAN-24-YL]AMINO)ETHANESULFONIC ACID
• 5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
• NSC681055
• 2-([3α,7α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt
• Taurochenodeoxycholic acid sodium salt, 2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
• 5BETA-CHOLANIC ACID-3ALPHA,7ALPHA-DIOL-24-N-(2-SULFOETHYL)-AMIDE SODIUM

Ethanesulfonic acid, 2-[[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)

CAS: 6009-98-9

Formula: C₂₆H₄₄NNaO₆S

Purity: 97%

Color and Shape: Solid

Molecular weight: 521.6854

Ref: IN-DA0035MQ

Taurochenodeoxycholic acid sodium

CAS: 6009-98-9

Taurochenodeoxycholic acid sodium

Purity: ≥95%

Molecular weight: 521.68g/mol

Ref: 54-BUP16477

Sodium taurochenodeoxycholate

CAS: 6009-98-9

Formula: C₂₆H₄₄NNaO₆S

Purity: ≥ 97.0%

Color and Shape: White to off-white or light-beige powder

Molecular weight: 521.69

Ref: 7W-GL4583

Tauro-d4-chenodeoxycholic Acid Sodium Salt

CAS: 6009-98-9

Purity: 99 atom % D

Molecular weight: 525.71

Ref: 3U-D8183

Taurochenodeoxycholic acid sodium

CAS: 6009-98-9

Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).

Formula: C₂₆H₄₄NNaO₆S

Purity: 98.23% - 99.56%

Color and Shape: White To Off-White Powder

Molecular weight: 521.68

Ref: TM-TN2215

Taurochenodeoxycholic Acid Sodium Salt

Controlled Product

CAS: 6009-98-9

Applications Taurochenodeoxycholic Acid Sodium Salt is a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
References Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967); Takikawa, Y. et al.: Falk Symp., 120, 249 (2001); Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (2008);

Formula: C₂₆H₄₄NO₆S·Na

Color and Shape: White To Off-White

Molecular weight: 521.69

Ref: TR-T008130

Taurochenodeoxycholic Acid-d5 Sodium Salt

Controlled Product

CAS: 6009-98-9

Stability Hygroscopic
Applications Taurochenodeoxycholic Acid-d5 (Major) Sodium Salt is the labelled analogue of Taurochenodeoxycholic Acid (T008130), a bile acid conjugate and metabolite Taurolithocholic Acid (T009100) with antiinflammatory activity. Taurochenodeoxycholic Acid has been shown to inhibit hepatocyte apoptosis through suppression of Bid translocation to mitochondria.
References Emerman, S. et al.: J. Biol. Chem., 242, 661 (1967); Takikawa, Y. et al.: Falk Symp., 120, 249 (2001); Li, P. et al.: Zhong. Shour. Xue., 28, 1317 (2008)

Formula: C₂₆H₃₉D₅NNaO₆S

Color and Shape: White To Beige

Molecular weight: 526.72

Ref: TR-T008133

Taurochenodeoxycholic acid sodium

CAS: 6009-98-9

Taurochenodeoxycholic acid sodium is a bile acid derivative, which is naturally sourced from the bile of mammals. It is synthesized by conjugating chenodeoxycholic acid with taurine, resulting in its sodium salt form. The primary mode of action of taurochenodeoxycholic acid sodium involves its role in the emulsification and absorption of dietary fats and fat-soluble vitamins in the intestines. Additionally, it acts on the liver, where it enhances bile flow and exhibits hepatoprotective properties by modulating bile acid composition and reducing cytotoxicity.

Formula: C₂₆H₄₅NO₆S•Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 522.7 g/mol

Ref: 3D-FT147865

Sodium Taurochenodeoxycholate (STCDC) extrapure, 95%

CAS: 6009-98-9

Formula: C₂₆H₄₄NNaO₆S

Purity: min. 95%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 521.69

Ref: SR-58529