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CAS 6014-43-3

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Strophanthidin-β-D-glucopyranoside

Description:
Strophanthidin-β-D-glucopyranoside is a glycoside derived from strophanthidin, which is a cardiac glycoside. This compound is characterized by its structure, which includes a steroid nucleus and a glucose moiety linked through a glycosidic bond. It exhibits biological activity, particularly in its ability to influence cardiac function, making it of interest in pharmacology. Strophanthidin-β-D-glucopyranoside can affect ion transport across cell membranes, particularly influencing sodium and potassium ion dynamics, which is crucial for cardiac muscle contraction. The compound is typically found in certain plant species, particularly those in the Apocynaceae family. Its solubility properties can vary, often being more soluble in polar solvents. As with many glycosides, it may exhibit varying degrees of toxicity and pharmacological effects, necessitating careful handling and consideration in therapeutic contexts. Overall, its unique structure and biological activity make it a subject of interest in both natural product chemistry and medicinal research.
Formula:C29H42O11
InChI:InChI=1S/C29H42O11/c1-26-6-3-18-19(29(26,37)9-5-17(26)15-10-21(32)38-13-15)4-8-28(36)11-16(2-7-27(18,28)14-31)39-25-24(35)23(34)22(33)20(12-30)40-25/h10,14,16-20,22-25,30,33-37H,2-9,11-13H2,1H3/t16-,17+,18-,19+,20+,22+,23-,24+,25+,26+,27-,28-,29-/m0/s1
InChI key:InChIKey=UWXGONCJXIMJRE-BETXHDQMSA-N
SMILES:C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C5=CC(=O)OC5)(CC[C@]1(O)C[C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)CC2)[H])[H]
Synonyms:
  • Glucostrophanthidin
  • (3β,5β)-3-(β-D-Glucopyranosyloxy)-5,14-dihydroxy-19-oxocard-20(22)-enolide
  • Strophanthidin, 3-β-D-glucoside
  • 5β-Card-20(22)-enolide, 3β-(β-D-glucopyranosyloxy)-5,14-dihydroxy-19-oxo-
  • Card-20(22)-enolide, 3-(β-D-glucopyranosyloxy)-5,14-dihydroxy-19-oxo-, (3β,5β)-
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Found 1 products.
  • Glucostrophanthidin
    Biosynth
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    Glucostrophanthidin

    CAS:
    <p>Glucostrophanthidin is a cardiac glycoside, which is derived from natural plant sources, specifically from species in the Apocynaceae family. This compound exerts its effects primarily through inhibition of the sodium-potassium ATPase enzyme, leading to an increase in intracellular sodium concentration. The downstream effect of this process involves an increase in intracellular calcium via the sodium-calcium exchange mechanism, ultimately enhancing the contractility of cardiac muscle fibers.</p>
    Formula:C29H42O11
    Purity:Min. 95%
    Molecular weight:566.64 g/mol

    Ref: 3D-FG163243

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