CAS 60197-30-0
:5-(2-amino-2-oxoethyl)-2'-O-methyluridine
Description:
5-(2-amino-2-oxoethyl)-2'-O-methyluridine, also known by its CAS number 60197-30-0, is a modified nucleoside that features a uridine base with specific structural modifications. This compound includes an amino group and a carbonyl group at the 2-position of the ribose sugar, contributing to its unique biochemical properties. The presence of the 2'-O-methyl group enhances its stability against enzymatic degradation, making it of interest in various biochemical applications, including RNA research and therapeutic development. Its structural modifications can influence its interaction with nucleic acids, potentially affecting binding affinity and specificity. Additionally, this nucleoside may exhibit unique pharmacological properties, making it a candidate for further investigation in drug design and molecular biology studies. Overall, 5-(2-amino-2-oxoethyl)-2'-O-methyluridine represents a significant compound in the field of nucleoside chemistry, with implications for both basic research and therapeutic applications.
Formula:C12H17N3O7
InChI:InChI=1/C12H17N3O7/c1-21-9-8(18)6(4-16)22-11(9)15-3-5(2-7(13)17)10(19)14-12(15)20/h3,6,8-9,11,16,18H,2,4H2,1H3,(H2,13,17)(H,14,19,20)/t6-,8-,9-,11-/m1/s1
SMILES:CO[C@@H]1[C@@H]([C@@H](CO)O[C@H]1n1cc(CC(=N)O)c(nc1=O)O)O
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Found 2 products.
5-Carbamoylmethyl-2'-O-methyluridine
CAS:Controlled ProductFormula:C12H17N3O7Color and Shape:NeatMolecular weight:315.285-Carbamoylmethyl-2'-O-methyluridine
CAS:<p>5-Carbamoylmethyl-2'-O-methyluridine is a nucleoside analog that inhibits the synthesis of proteins by inhibiting the translation process. It has been shown to be effective against tuberculosis and other mycobacterial diseases. 5-Carbamoylmethyl-2'-O-methyluridine binds to the ribosomal RNA, preventing protein synthesis and causing cell death. This drug has pleiotropic effects on cells, including inhibition of frameshifting, which is a mechanism used by some viruses to avoid immune responses. 5-Carbamoylmethyl-2'-O-methyluridine also interacts with cellular genes in response to stress (e.g., ultraviolet radiation). The mechanism of action for this drug is similar to that of 5-methoxycarbonylmethyl 2'-thiouridine (5MMCU), which inhibits protein synthesis by binding to the 30S ribosomal subunit and blocking the formation of</p>Formula:C12H17N3O7Purity:Min. 95%Color and Shape:PowderMolecular weight:315.28 g/mol

