CAS 60200-06-8

clorsulon

Description:

Clorsulon is a synthetic sulfonamide compound primarily used as an anthelmintic agent, particularly in veterinary medicine for the treatment of liver fluke infections in livestock. It is characterized by its broad-spectrum efficacy against various trematodes, particularly Fasciola hepatica. Clorsulon functions by inhibiting the enzyme phosphofructokinase, disrupting the glycolytic pathway in the parasites, which ultimately leads to their death. The compound is typically administered orally and is known for its low toxicity to mammals, making it a safe option for treating infected animals. Clorsulon is often used in combination with other antiparasitic agents to enhance its effectiveness and reduce the likelihood of resistance development. Its chemical structure features a sulfonamide group, which is integral to its mechanism of action. Additionally, clorsulon is stable under normal storage conditions, contributing to its practicality in veterinary applications. Overall, clorsulon represents an important tool in managing parasitic infections in livestock, contributing to animal health and agricultural productivity.

Formula: C₈H₈Cl₃N₃O₄S₂

InChI: InChI=1/C8H8Cl3N3O4S2/c9-7(8(10)11)3-1-4(12)6(20(14,17)18)2-5(3)19(13,15)16/h1-2H,12H2,(H2,13,15,16)(H2,14,17,18)

InChI key: InChIKey=QOVTVIYTBRHADL-UHFFFAOYSA-N

SMILES: C(=C(Cl)Cl)(Cl)C1=C(S(N)(=O)=O)C=C(S(N)(=O)=O)C(N)=C1

Synonyms:

• 1,3-Benzenedisulfonamide, 4-amino-6-(1,2,2-trichloroethenyl)-
• 1,3-Benzenedisulfonamide, 4-amino-6-(trichloroethenyl)-
• 4-Amino-6-(1,2,2-trichloroethenyl)-1,3-benzenedisulfonamide
• 4-Amino-6-(Trichloroethenyl)-3-Benzenedisulfonamide
• 4-Amino-6-(Trichloroethenyl)Benzene-1,3-Disulfonamide
• 4-Amino-6-(Trichlorovinyl)-1,3-Benzenedisulfonamide
• 4-Amino-6-(Trichlorovinyl)-M-Benzenedisulfonamide
• 4-Amino-6-(trichloroethenyl)-1,3-benzenedisulfonamide
• Curatrem
• L 631529
• Mk 401
• l631529
• 4-AMINO-6-(TRICHLOROETHENYL)-1,3-BENZENEDISULPHONAMIDE
• CLORSULON USP
• CLORSULON
• 4-AMINO-6-(1,2,2-TRICHLOROVINYL)BENZENE-1,3-DISULFONAMIDE
• 4-AMINO-6-(TRICHLORO-ETHENYL)-1,3-BENZENEDISULFONAMIDE
• Foramsulfuron, Pestanal

Clorsulon

CAS: 60200-06-8

Color and Shape: Neat

Ref: 61-FOR1518.00

Clorsulon

CAS: 60200-06-8

Sulfonamides used as drugs

Formula: C₈H₈Cl₃N₃O₄S₂

Color and Shape: White Powder

Molecular weight: 378.90218

Ref: 45-1140702

Clorsulon

CAS: 60200-06-8

Clorsulon (L631529) is utilized for the treatment of Fasciola hepatica infections in calves and sheep.

Formula: C₈H₈Cl₃N₃O₄S₂

Purity: 99.66% - 99.87%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 380.66

Ref: TM-T1137

Clorsulon

CAS: 60200-06-8

Clorsulon

Purity: 98%

Molecular weight: 380.66g/mol

Ref: 54-OR1030249

Clorsulon

CAS: 60200-06-8

Clorsulon

Purity: ≥98%

Molecular weight: 380.66g/mol

Ref: 54-BUP16706

Clorsulon

CAS: 60200-06-8

Formula: C₈H₈Cl₃N₃O₄S₂

Color and Shape: Neat

Molecular weight: 380.66

Ref: 86-MM1518.00

Clorsulon

CAS: 60200-06-8

Formula: C₈H₈Cl₃N₃O₄S₂

Purity: >98.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 380.64

Ref: 3B-C3821

Clorsulon 1000 µg/mL in Acetonitrile

Controlled Product

CAS: 60200-06-8

Formula: C₈H₈Cl₃N₃O₄S₂

Color and Shape: Single Solution

Molecular weight: 380.66

Ref: 04-A11691400AL-1000

Clorsulon

CAS: 60200-06-8

Formula: C₈H₈Cl₃N₃O₄S₂

Color and Shape: Neat

Molecular weight: 380.66

Ref: 04-C11691400

Clorsulon

CAS: 60200-06-8

Formula: C₈H₈Cl₃N₃O₄S₂

Molecular weight: 380.66

Ref: 4Z-C-232001

Clorsulon

Controlled Product

CAS: 60200-06-8

Applications A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes).
References Mrozik, H., et al.: J. Med. Chem., 20, 1225 (1977), Ostlind, D.A., et al.: Br. Vet. J., 133, 211 (1977), Schulman, M.D., et al.: J. Parasitol., 65, 555 (1979),

Formula: C₈H₈Cl₃N₃O₄S₂

Color and Shape: Neat

Molecular weight: 380.66

Ref: TR-C587380

Clorsulon

CAS: 60200-06-8

Clorsulon is an anthelmintic drug that belongs to the group of benzimidazoles. It is used in veterinary medicine to treat nematode and cestode infections, as well as tapeworm infections. Clorsulon is a dispersive solid-phase extraction (DSPE) extractant that can be used for the separation of drugs and their metabolites from biological fluids. The chemical stability of clorsulon was assessed by exposing it to various solvents and pHs. Clorsulon was found to be stable in acetate, benzene, chloroform, ethyl acetate, ethanol, methanol, and water at pH 1-14 and a variety of temperatures ranging from -20 ˚C to 50 ˚C. No significant loss or degradation occurred after exposure to these conditions for up to 24 hours.

Formula: C₈H₈Cl₃N₃O₄S₂

Purity: (Hplc) Min. 98.0%

Color and Shape: Powder

Molecular weight: 380.66 g/mol

Ref: 3D-FA20519