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CAS 60203-57-8

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PGJ2

Description:
PGJ2, or Prostaglandin J2, is a naturally occurring prostaglandin derived from the metabolism of arachidonic acid. It is characterized by its role as a bioactive lipid mediator involved in various physiological processes, including inflammation, cell proliferation, and apoptosis. PGJ2 is known for its ability to activate peroxisome proliferator-activated receptors (PPARs), particularly PPAR-gamma, which plays a crucial role in regulating glucose metabolism and adipocyte differentiation. This compound exhibits anti-inflammatory properties and has been studied for its potential therapeutic effects in conditions such as diabetes, obesity, and cancer. Additionally, PGJ2 can undergo spontaneous conversion to other biologically active forms, contributing to its diverse biological effects. Its chemical structure features a cyclopentane ring and multiple double bonds, which are essential for its biological activity. Due to its potent effects, PGJ2 and its derivatives are of significant interest in pharmacological research and therapeutic applications.
Formula:C20H30O4
InChI:InChI=1/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-13+/t16-,17-,18+/m0/s1
InChI key:InChIKey=UQOQENZZLBSFKO-POPPZSFYSA-N
SMILES:C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@H](C/C=C\CCCC(O)=O)C=CC1=O
Synonyms:
  • (5Z,13E,15S)-15-hydroxy-11-oxoprosta-5,9,13-trien-1-oic acid
  • 9,10-Didehydro-9-deoxy-PGD<sub>2</sub>
  • 9-Deoxy-delta-9-pgd2
  • 9-Deoxy-delta-9-prostaglandin D2
  • PGJ<sub>2</sub>
  • Pgj2
  • Prosta-5,9,13-trien-1-oic acid, 15-hydroxy-11-oxo-, (5Z,13E,15S)-
  • Prostaglandin J<sub>2</sub>
  • 9,10-Didehydro-9-deoxy-PGD2
  • Prostaglandin J2
  • See more synonyms
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Found 3 products.
  • Prostaglandin J2
    Indagoo
    + Info

    Prostaglandin J2

    CAS:
    Formula:C20H30O4
    Purity:95%，5 mg/mL in methyl acetate
    Color and Shape:Liquid
    Molecular weight:334.4498

    Ref: IN-DA00EB4E

    1mg
    To inquire
  • Prostaglandin J2
    Targetmol
    + Info

    Prostaglandin J2

    CAS:
    PGJ2, a PGD2 metabolite, is a DP agonist (Ki: 0.9 nM hDP, 6.6 nM hCRTH2), induces cAMP (EC50: 1.2 nM), oxidative stress, neuronal apoptosis, and neurotoxicity.
    Formula:C20H30O4
    Color and Shape:Solid
    Molecular weight:334.45

    Ref: TM-T73782

    1mg
    540.00€
    5mg
    2,300.00€
    10mg
    4,019.00€
    500µg
    283.00€
  • PGJ2 (Prostaglandin J2)
    TRC
    + Info

    PGJ2 (Prostaglandin J2)

    Controlled Product
    CAS:
    Formula:C20H30O4
    Color and Shape:Neat
    Molecular weight:334.45

    Ref: TR-P294203

    50mg
    10,511.00€