CAS 60205-81-4: Ipratropium

Description: Ipratropium is a synthetic quaternary ammonium compound primarily used as a bronchodilator in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It functions as an anticholinergic agent, inhibiting the action of acetylcholine on muscarinic receptors in the airways, leading to relaxation of bronchial smooth muscle and improved airflow. Ipratropium is typically administered via inhalation, allowing for localized effects in the lungs with minimal systemic absorption. The substance is characterized by its relatively low solubility in water, which influences its formulation in aerosol or nebulizer solutions. It has a molecular formula that includes nitrogen and exhibits a positive charge at physiological pH, contributing to its pharmacological properties. Ipratropium is often used in combination with other bronchodilators, such as beta-agonists, to enhance therapeutic efficacy. Its safety profile is well-established, with common side effects including dry mouth and throat irritation, while serious adverse effects are rare. Overall, Ipratropium is a vital medication in managing obstructive airway diseases.

Formula: C₂₀H₃₀NO₃

InChI: InChI=1/C20H30NO3/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15/h4-8,14,16-19,22H,9-13H2,1-3H3/q+1/t16-,17+,18+,19?,21+

InChI key: InChIKey=OEXHQOGQTVQTAT-JRNQLAHRNA-N

SMILES: O=C(OC1CC2CCC(C1)[N+]2(C)C(C)C)C(C=3C=CC=CC3)CO

Synonyms:

• (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, (3-endo,8-syn)-
• Ipratropium
• 8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, (endo,syn)-(±)-
• (±)-Ipratropine

Ipratropium Bromide Monohydrate

CAS: 22254-24-6 60205-81-466985-17-9

• Formula: C₂₀H₃₀BrNO₃·H₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 430.39

Ipratropium Bromide

CAS: 60205-81-4

• Formula: C₂₀H₃₀NO₃·Br
• Molecular weight: 332.46 79.90

Ipratropium Free Base

CAS: 60205-81-4

Ipratropium, safer than Atropine, is an inhalable muscarinic antagonist used for bronchial issues, rhinitis, and …

• Formula: C₂₀H₃₀NO₃
• Color and Shape: Liquid
• Molecular weight: 332.46

Ipratropium-d3 Iodide

CAS: 60205-81-4

Applications N-Isopropyl quaternary salt of Atropine. Nonselective muscarinic acetylcholine receptor antagonist; bronchodilator. References Groeben, H., …

• Formula: C₂₀H₂₇D₃INO₃
• Color and Shape: Neat
• Molecular weight: 462.38

Ipratropium-d3 iodide

CAS: 60205-81-4

Please enquire for more information about Ipratropium-d3 iodide including the price, delivery time and more …

• Formula: C₂₀H₃₀NO₃
• Purity: Min. 95%
• Molecular weight: 332.5 g/mol