CAS 60227-09-0

Medermycin

Description:

Medermycin, with the CAS number 60227-09-0, is an antibiotic compound belonging to the class of macrolides. It is primarily known for its antibacterial properties, particularly against certain Gram-positive bacteria. Medermycin exhibits a unique mechanism of action by inhibiting bacterial protein synthesis, which is crucial for bacterial growth and reproduction. This compound is often utilized in veterinary medicine, particularly for treating infections in livestock and poultry. Its structure features a large lactone ring, characteristic of macrolide antibiotics, which contributes to its biological activity. Medermycin is typically administered in various formulations, including injectables and oral preparations, depending on the target species and type of infection. As with many antibiotics, the potential for resistance development is a concern, necessitating careful use and adherence to veterinary guidelines. Overall, Medermycin represents an important tool in the management of bacterial infections in animals, contributing to improved health and productivity in agricultural settings.

Formula: C₂₄H₂₇NO₈

InChI: InChI=1/C24H27NO7/c1-10-19-20(24-17(30-10)9-18(26)32-24)22(28)13-6-5-12(7-14(13)23(19)29)16-8-15(25(3)4)21(27)11(2)31-16/h5-7,10-11,15-17,21,24,27H,8-9H2,1-4H3/t10-,11-,15-,16?,17-,21-,24+/m1/s1

Synonyms:

• [3aS,(-)]-3,3aβ,5,11bβ-Tetrahydro-7-hydroxy-5β-methyl-8-[3-(dimethylamino)-2,3,6-trideoxy-L-arabino-hexopyranosyl]-2H-furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione
• Medermycin
• Lactoquinomycin
• 2H-Furo[3,2-b]naphtho[2,3-d]pyran-2,6,11-trione, 3,3a,5,11b-tetrahydro-7-hydroxy-5-methyl-8-[2,3,6-trideoxy-3-(dimethylamino)-β-D-arabino-hexopyranosyl]-, (3aR,5R,11bR)-

Medermycin

CAS: 60227-09-0

Lactoquinomycin A is a quinone antibiotic displaying activity against Gram-positive bacteria and some Gram-negative bacteria, though its efficacy is weaker against the latter and it is ineffective against fungi. It inhibits various cell lines, including lymphoma L5178Y progenitor cells, doxorubicin-resistant cells, bleomycin-resistant cells, human leukemia K562 cells, murine leukemia L-1210 cells, and murine leukemia P388 cells, with ID50 values (μg/mL) of 0.02, 0.006, 0.008, 0.033, 0.013, and 0.03, respectively.

Formula: C₂₄H₂₇NO₈

Color and Shape: Solid

Molecular weight: 457.473

Ref: TM-TN10069