CAS 60254-95-7

R 19167

Description:

R 19167, also known by its CAS number 60254-95-7, is a chemical compound that belongs to the class of synthetic organic compounds. It is primarily recognized for its application in the field of pharmaceuticals, particularly as an intermediate in the synthesis of various medicinal agents. The compound exhibits specific characteristics such as being a solid at room temperature, with a defined melting point and solubility profile that typically allows it to dissolve in organic solvents. R 19167 may also possess functional groups that contribute to its reactivity and interaction with biological systems. Safety data sheets indicate that it should be handled with care, as it may pose health risks if ingested or inhaled, necessitating the use of appropriate personal protective equipment during handling. Its chemical structure and properties make it a subject of interest in research and development, particularly in the context of drug formulation and synthesis.

Formula: C₁₆H₁₅N₃O₃

InChI: InChI=1S/C16H15N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9,14,20H,1H3,(H2,17,18,19,21)

InChI key: InChIKey=IIQKUGXEGMZCLE-UHFFFAOYSA-N

SMILES: C(O)(C=1C=C2C(N=C(NC(OC)=O)N2)=CC1)C3=CC=CC=C3

Synonyms:

• 5-Hydroxymebendazole
• R 19167
• Carbamic acid, [5-(hydroxyphenylmethyl)-1H-benzimidazol-2-yl]-, methyl ester
• Carbamic acid, N-[6-(hydroxyphenylmethyl)-1H-benzimidazol-2-yl]-, methyl ester

5-Hydroxymebendazole

CAS: 60254-95-7

5-Hydroxymebendazole

Purity: ≥98%

Molecular weight: 297.31g/mol

Ref: 54-BUP21279

Mebendazole-5-hydroxy

CAS: 60254-95-7

Formula: C₁₆H₁₅N₃O₃

Color and Shape: Light Yellow

Molecular weight: 297.31

Ref: 04-C14798020

5-Hydroxymebendazole

CAS: 60254-95-7

5-Hydroxymebendazole (HMBZ) is a metabolite of mebendazole. Mebendazole is a broad-spectrum antiparasitic compound.

Formula: C₁₆H₁₅N₃O₃

Purity: 99.25%

Color and Shape: Solid

Molecular weight: 297.31

Ref: TM-T29458

5-Hydroxymebendazole

CAS: 60254-95-7

Formula: C₁₆H₁₅N₃O₃

Molecular weight: 297.32

Ref: 4Z-M-618

rac Dihydro Mebendazole

CAS: 60254-95-7

Applications The reduced metabolite of Mebendazole (M200500).
References Facino, R., et al.: Biol. Mass Spectrom, 21, 195 (1992), Iosifidou, E., et al.: Drug Metab. Dispos., 25, 317 (1997), De Ruyck, H., et al.: J. Agric. Food Chem., 49, 610 ( 2001),

Formula: C₁₆H₁₅N₃O₃

Color and Shape: Light Yellow

Molecular weight: 297.31

Ref: TR-D449320

5-Hydroxymebendazole

CAS: 60254-95-7

5-Hydroxymebendazole is a benzimidazole compound that is used as an anthelmintic. It has been shown to have efficacy against a number of parasites, including those that infest the central nervous system (CNS), such as the brain tumor. 5-Hydroxymebendazole has also been shown to be effective in the treatment of clostridial infections and other diseases caused by macrolide-resistant bacteria. This molecule has been validated for use in liquid chromatography with mass spectrometry (LC-MS) for determining its concentration in urine samples. The sample preparation procedure includes extraction and derivatization of 5-hydroxymebendazole, followed by analysis using LC-MS/MS. The calibration curve was generated using standards with concentrations ranging from 0.1 µg/mL to 10 µg/mL, and validation was accomplished by comparing results obtained with this method to those obtained following the standard procedure for

Formula: C₁₆H₁₅N₃O₃

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 297.31 g/mol

Ref: 3D-FH61716

5-Hydroxymebendazole

CAS: 60254-95-7

Formula: C₁₆H₁₅N₃O₃

Molecular weight: 297.31

Ref: ST-EA-CP-M7013

Mebendazole-5-hydroxy 100 µg/mL in Acetonitrile:Dimethylsulfoxide

CAS: 60254-95-7

Formula: C₁₆H₁₅N₃O₃

Color and Shape: Single Solution

Molecular weight: 297.31

Ref: 04-A14798020DL-100