CAS 6027-83-4

3′-Guanylic acid, sodium salt (1:2)

Description:

3′-Guanylic acid, sodium salt (1:2), commonly referred to as sodium guanylate, is a nucleotide derivative that plays a significant role in cellular processes, particularly in the synthesis of RNA and as a signaling molecule. It is characterized by its guanine base, ribose sugar, and phosphate group, which are essential for its biological functions. As a sodium salt, it is soluble in water, making it useful in various biochemical applications. Sodium guanylate is often utilized as a flavor enhancer in the food industry, similar to monosodium glutamate (MSG), due to its ability to enhance umami taste. In addition to its culinary uses, it is also studied for its potential roles in cellular signaling pathways and as a supplement in certain therapeutic contexts. The compound is generally recognized as safe when used appropriately, but like any additive, it should be consumed within recommended limits. Its stability and reactivity are influenced by environmental factors such as pH and temperature, which are important considerations in both laboratory and industrial settings.

Formula: C₁₀H₁₄N₅O₈P·2Na

InChI: InChI=1S/C10H14N5O8P.2Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-5(17)6(3(1-16)22-9)23-24(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3,11,13,14,18);;/t3-,5-,6-,9-;;/m1../s1

InChI key: InChIKey=CGQAIYAEMBAVGK-LGVAUZIVSA-N

SMILES: O[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)O[C@H](CO)[C@H]1OP(=O)(O)O.[Na]

Synonyms:

• 2,2'-[(1E,3Z,5E)-5-(3-heptyl-4-methyl-1,3-thiazol-2(3H)-ylidene)penta-1,3-diene-1,3-diyl]bis(3-heptyl-4-methyl-1,3-thiazol-3-ium) dichloride
• 3′-Guanylic acid, disodium salt
• 3′-Guanylic acid, sodium salt (1:2)
• Disodium 3′-GMP
• Guanosine 3(+2)-monophosphate disodium salt
• Guanosine-2-(3)monophosphoric acid disodium salt

3′-Guanylic acid disodium

CAS: 6027-83-4

3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.

Formula: C₁₀H₁₄N₅O₈P•Na₂

Purity: Min. 95%

Molecular weight: 409.2 g/mol

Ref: 3D-NG182606

Guanosine-2'(&3')-monophosphate disodium (mixed isomers)

CAS: 6027-83-4

Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is a synthetic nucleoside with antiviral and anticancer properties. It has been shown to activate the transcription of DNA in vitro by binding to the promoter region, resulting in higher levels of RNA synthesis. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) has been shown to inhibit the replication of viruses, such as herpes simplex virus type 1 (HSV-1), and it may have potential use in cancer therapy. The drug is also used as a precursor for other antiviral drugs and antibiotics. Guanosine-2'(&3')-monophosphate disodium salt (mixed isomers) is available in high purity, high quality, and at low cost.

Formula: C₁₀H₁₄N₅O₈P•2Na

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 407.18 g/mol

Ref: 3D-NG57356