CAS 6027-91-4

3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1)

Description:

3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1), commonly referred to as a pyridine derivative, is characterized by its structural features that include a pyridine ring and a carboxylic acid functional group. This compound typically appears as a white to off-white crystalline solid and is soluble in water due to the presence of the hydrochloride salt form, which enhances its solubility compared to the free base. The presence of the tetrahydro configuration indicates that the compound has undergone partial saturation, affecting its reactivity and interaction with biological systems. It may exhibit properties such as being a weak acid, with potential applications in pharmaceuticals or as a biochemical reagent. The hydrochloride form often enhances stability and bioavailability, making it useful in various chemical and biological applications. As with many pyridine derivatives, it may also exhibit specific pharmacological activities, although detailed studies would be necessary to elucidate its full range of properties and potential uses.

Formula: C₆H₉NO₂·ClH

InChI: InChI=1S/C6H9NO2.ClH/c8-6(9)5-2-1-3-7-4-5;/h2,7H,1,3-4H2,(H,8,9);1H

InChI key: InChIKey=FGNUNVVTHHKDAM-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=CCCNC1.Cl

Synonyms:

• 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride (1:1)
• 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-, hydrochloride
• Nicotinic acid, 1,2,5,6-tetrahydro-, hydrochloride
• 1,2,5,6-Tetrahydropyridine-3-carboxylic acid hydrochloride
• Guvacine, hydrochloride

1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride

CAS: 6027-91-4

Formula: C₆H₁₀ClNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 163.6021

Ref: IN-DA00EEUZ

Guvacine hydrochloride

CAS: 6027-91-4

Formula: C₆H₉NO₂·HCl

Molecular weight: 163.60

Ref: 7W-GL7856

Guvacine hydrochloride

CAS: 6027-91-4

Guvacine hydrochloride

Purity: ≥98%

Molecular weight: 163.602g/mol

Ref: 54-BUP11031

Guvacine HCl

CAS: 6027-91-4

Formula: C₆H₉NO₂(FreeBase)

Purity: 95%~99%

Molecular weight: 127.143

Ref: BP-BP4087

Guvacine HCl

CAS: 6027-91-4

Formula: C₆H₉NO₂·HCl

Molecular weight: 127.14 36.46

Ref: 4Z-G-224001

Guvacine hydrochloride

CAS: 6027-91-4

Guvacine hydrochloride is an inhibits of GABA uptake (IC50 : 10 μM)

Formula: C₆H₁₀ClNO₂

Purity: 98.42%

Color and Shape: Solid

Molecular weight: 163.602

Ref: TM-T7557

Guvacine hydrochloride

CAS: 6027-91-4

Natural alkaloid

Formula: C₆H₉NO₂HCl

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 163.6

Ref: 5G-85879

Guvacine Hydrochloride

Controlled Product

CAS: 6027-91-4

Applications Guvacine Hydrochloride is a GABA uptake inhibitor (hGABA T-1, rGABA T-2, hGABA T-3 and hBGT-1) (1,2,3). Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain (4). Guvacine Hydrochloride may be useful for treating neuropsychiatric disorders.
References (1) Lesnefsky, E., et al.: J. Biol. Chem., 279, 47961 (2004) (2) Nadtochiy, S., et al.: Biochem. J., 395, 611 (2006) (3) Corns, L.F., et al.: Neurosci Lett. 553, 57 (2013). (4) Borden, L. A., et al.: Eur J Pharmacol. 269, 219 (1994)

Formula: C₆H₉NO₂·ClH

Color and Shape: Neat

Molecular weight: 163.60

Ref: TR-G876400

1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HCL

CAS: 6027-91-4

Purity: 95%

Molecular weight: 163.6000061

Ref: 10-F824159

Guvacine-2,2,5,5-D4 Hydrochloride

Controlled Product

CAS: 6027-91-4

Formula: C₆H₅D₄NO₂•(HCl)

Color and Shape: Neat

Molecular weight: 167.06511

Ref: TR-G876402