CAS 60314-89-8

Geissoschizine methyl ether

Description:

Geissoschizine methyl ether is a naturally occurring alkaloid derived from the plant species Geissospermum, which is known for its traditional medicinal uses. This compound is characterized by its complex molecular structure, which includes a bicyclic framework typical of many alkaloids. It exhibits a range of biological activities, including potential anti-inflammatory and analgesic properties, making it of interest in pharmacological research. Geissoschizine methyl ether is typically studied for its effects on various biological systems, including its interaction with neurotransmitter receptors. The compound is soluble in organic solvents, which facilitates its extraction and purification from plant sources. Its chemical properties, such as melting point and solubility, can vary based on environmental conditions and the specific extraction methods used. As with many alkaloids, caution is advised in handling due to potential toxicity and the need for further research to fully understand its pharmacodynamics and therapeutic potential.

Formula: C₂₂H₂₆N₂O₃

InChI: InChI=1S/C22H26N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h4-8,13,17,20,23H,9-12H2,1-3H3/b14-4-,18-13-/t17-,20-/m0/s1

InChI key: InChIKey=VAMJZLUOKJRHOW-XEASWFAXSA-N

SMILES: C(\C(OC)=O)(=C\OC)/[C@H]/1C[C@]2(C3=C(C=4C(N3)=CC=CC4)CCN2C\C1=C\C)[H]

Synonyms:

• Geissoschizine methyl ether
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, [2S-[2α(Z),3E,12bβ]]-
• O-Methyl-16Z-geissoschizine
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethylidene-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αZ,2S,3E,12bS)-
• Corynan-16-carboxylic acid, 16,17,19,20-tetradehydro-17-methoxy-, methyl ester, (16Z,19E)-

Geissoschizine methyl ether

CAS: 60314-89-8

Formula: C₂₂H₂₆N₂O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 366.4534

Ref: IN-DA00ILVG

Geissoschizine methyl ether

CAS: 60314-89-8

Formula: C₂₂H₂₆N₂O₃

Molecular weight: 366.46

Ref: 7W-GY8518

Geissoschizine methyl ether

CAS: 60314-89-8

Geissoschizine methyl ether

Purity: ≥98%

Molecular weight: 366.45g/mol

Ref: 54-BUP03675

Geissoschizine methyl ether

CAS: 60314-89-8

Formula: C₂₂H₂₆N₂O₃

Purity: 95%~99%

Molecular weight: 366.461

Ref: BP-BP3924

Geissoschizine methyl ether

CAS: 60314-89-8

Geissoschizine methyl ether: an alkaloid from Uncaria hook, key in Yokukansan, impacts mood and social behavior enhancing serotonin activity.

Formula: C₂₂H₂₆N₂O₃

Purity: 99.24% - 99.68%

Color and Shape: Solid

Molecular weight: 366.45

Ref: TM-TN1032

Geissoschizine methyl ether

CAS: 60314-89-8

Geissoschizine methyl ether is a chemical compound that belongs to the group of 5-HT2C receptor antagonists. It is also known as geissoschizine methyl ether and uncaria. Geissoschizine methyl ether binds to the serotonin 5-HT2C receptor, which leads to an increase in intracellular calcium levels and subsequently neuronal death. In addition, this agent has been shown to inhibit voltage-dependent calcium channels, leading to a decrease in neurotransmitter release. The compound has also been shown to inhibit polymerase chain reaction (PCR) of DNA and RNA in vitro. This inhibition may be due to its ability to bind with basic proteins such as histones. Geissoschizine methyl ether also inhibits protein synthesis by binding with the ribosome at the peptidyl transferase site on the ribosome.

Formula: C₂₂H₂₆N₂O₃

Purity: Min. 95%

Molecular weight: 366.46 g/mol

Ref: 3D-KCA31489