CAS 604-33-1

Cholesteryl linoleate

Description:

Cholesteryl linoleate is an ester formed from cholesterol and linoleic acid, characterized by its role as a lipid component in biological membranes and its presence in various biological systems. It is a white to off-white solid at room temperature and is insoluble in water but soluble in organic solvents such as chloroform and ethanol. This compound is notable for its hydrophobic nature, which contributes to its function in membrane structure and fluidity. Cholesteryl linoleate serves as a storage form of linoleic acid, an essential fatty acid, and plays a role in cellular signaling and metabolism. Its presence in lipoproteins and cell membranes highlights its importance in lipid metabolism and cardiovascular health. Additionally, it can be involved in the formation of lipid droplets and may influence the physical properties of membranes, such as permeability and flexibility. Overall, cholesteryl linoleate is significant in both biochemistry and nutrition, reflecting the complex interplay between lipids and biological functions.

Formula: C₄₅H₇₆O₂

InChI: InChI=1S/C45H76O2/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25-43(46)47-38-30-32-44(5)37(34-38)26-27-39-41-29-28-40(36(4)24-22-23-35(2)3)45(41,6)33-31-42(39)44/h11-12,14-15,26,35-36,38-42H,7-10,13,16-25,27-34H2,1-6H3/b12-11-,15-14-/t36-,38+,39+,40-,41+,42+,44+,45-/m1/s1

InChI key: InChIKey=NAACPBBQTFFYQB-LJAITQKLSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCCC(C)C)C)(CC4)[H])[H])(CC=C1C[C@@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CC2)[H])[H]

Synonyms:

• (3beta)-cholest-5-en-3-yl (9Z,12Z)-octadeca-9,12-dienoate
• Cholest-5-en-3-ol (3β)-, (9Z,12Z)-9,12-octadecadienoate
• Cholest-5-en-3-ol (3β)-, 3-[(9Z,12Z)-9,12-octadecadienoate]
• Cholest-5-en-3-ol (3β)-, 9,12-octadecadienoate, (Z,Z)-
• Cholesterol linoleate
• Linoleic acid, cholesteryl ester
• NSC 18183
• cholest-5-en-3-yl (9E,12E)-octadeca-9,12-dienoate

Cholesterol Linoleate

CAS: 604-33-1

Formula: C₄₅H₇₆O₂

Purity: >95.0%(T)

Color and Shape: White to Orange to Green powder to lump

Molecular weight: 649.10

Ref: 3B-C0321

Cholesteryl linoleate

CAS: 604-33-1

Formula: C₄₅H₇₆O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 649.0837

Ref: IN-DA003OVI

Cholesteryl linoleate

CAS: 604-33-1

Cholesteryl linoleate

Purity: ≥98%

Molecular weight: 649.08g/mol

Ref: 54-BUP17999

Cholesteryl Linoleate

CAS: 604-33-1

Cholesteryl Linoleate

Purity: 95%

Molecular weight: 649.1g/mol

Ref: 54-OR1023618

Cholesteryl linoleate

CAS: 604-33-1

Formula: C₄₅H₇₆O₂

Molecular weight: 649.08

Ref: 7W-GL5675

Cholesteryl Linoleate

CAS: 604-33-1

Formula: C45H76O2

Purity: >99%

Color and Shape: Liquid

Molecular weight: 649.09

Ref: 48-64-1802

Cholesteryl linoleate

CAS: 604-33-1

Cholesteryl linoleate, a cholesterol ester in LDL, is moved to cell membranes and oxidized to hydroperoxides by 15-LO via LRP.

Formula: C₄₅H₇₆O₂

Purity: 99.61%

Color and Shape: Solid

Molecular weight: 649.08

Ref: TM-T5214

Cholesterol linoleate

Controlled Product

CAS: 604-33-1

Cholesterol linoleate is a model system that is used to study the role of cholesterol in atherosclerosis. It consists of a cholesterol-based polymer and linoleic acid, which are chemically similar to the natural lipids found in human cells. In vitro studies have shown that this model system has an inhibitory effect on ATP binding cassette transporter A1 (ABCA1) and ABCG1. These proteins transport cholesterol from cellular membranes to other parts of the cell, where they are degraded by enzymes called lysosomes. Cholesterol linoleate also inhibits basic protein, an enzyme that breaks down cholesteryl, leading to reduced levels of cholesteryl esters in the atheromatous lesions. This model system has been shown to reduce disease activity in animals with atherosclerotic lesions.

Formula: C₄₅H₇₆O₂

Color and Shape: White Powder

Molecular weight: 649.08 g/mol

Ref: 3D-FC61959