CAS 604-59-1

Alpha-Naphthoflavone

Description:

Alpha-Naphthoflavone, with the CAS number 604-59-1, is an organic compound that belongs to the class of flavonoids. It is characterized by its polycyclic structure, which consists of a flavone moiety fused to a naphthalene ring system. This compound typically appears as a yellow to orange crystalline solid and is known for its solubility in organic solvents such as ethanol and dimethyl sulfoxide, but it is less soluble in water. Alpha-Naphthoflavone exhibits various biological activities, including antioxidant properties and the ability to modulate enzyme activity, particularly in relation to cytochrome P450 enzymes. It has been studied for its potential effects on the metabolism of certain drugs and its role in the activation of various signaling pathways. Additionally, it has been used in research to investigate mechanisms of action related to carcinogenesis and the effects of environmental pollutants. Safety data indicates that, while it may pose some hazards, it is generally handled with standard laboratory precautions.

Formula: C₁₉H₁₂O₂

InChI: InChI=1/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H

InChI key: InChIKey=VFMMPHCGEFXGIP-UHFFFAOYSA-N

SMILES: O=C1C=2C(=C3C(=CC2)C=CC=C3)OC(=C1)C4=CC=CC=C4

Synonyms:

• 2-Phenyl-4H-naphtho[1,2-b]pyran-4-one
• 2-Phenylbenzo(H)Chromen-4-One
• 2-phenyl-4H-benzo[h]chromen-4-one
• 4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl-
• 7,8-Benzoflavone
• Benzo[h]flavone
• NSC 407011
• Uccf 023
• α-Naphthoflavone
• α-Naphthylflavone
• -Naphthoflavone
• 2-b)pyran-4-one,2-phenyl-4h-naphtho(
• BENZOFLAVONE
• NAPHTHOFLAVANONE, A-
• 1-Naphthoflavone
• alpha-naphthylflavone
• NAPHTHOFLAVONE, A-
• ALPHA-NAPHTHOFLAVONE REDOX INDICATOR
• alpha-Naphthoflavone,97%
• 2-b]pyran-4-one,2-phenyl-4h-naphtho[
• A-NAPHTHOFLAVANONE
• alfa-Naphthoflavone

α-Naphthoflavone

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 272.30

Ref: 3B-B0056

α-Naphthoflavone, 97%

CAS: 604-59-1

An aryl hydrocarbon receptor antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a pa

Formula: C₁₉H₁₂O₂

Purity: 97%

Color and Shape: White to pale cream, Powder

Molecular weight: 272.30

Ref: 02-A18542

7,8-Benzoflavone

CAS: 604-59-1

7,8-Benzoflavone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₉H₁₂O₂

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 272.31

Ref: 11-1008

2-Phenyl-4H-benzo[h]chromen-4-one

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 272.2974

Ref: IN-DA003VG1

α-Naphthoflavone

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Molecular weight: 272.31

Ref: 7W-GK0485

α-Naphthoflavone

CAS: 604-59-1

α-Naphthoflavone

Purity: ≥98%

Molecular weight: 272.3g/mol

Ref: 54-BUP10436

α-Naphthoflavone

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Purity: 95%~99%

Molecular weight: 272.303

Ref: BP-BP3065

α-Naphthoflavone

CAS: 604-59-1

alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.

Formula: C₁₉H₁₂O₂

Purity: 99.16% - 99.27%

Color and Shape: Yellow

Molecular weight: 272.3

Ref: TM-T2O2744

α-Naphthoflavone

CAS: 604-59-1

α-Naphthoflavone

Formula: C₁₉H₁₂O₂

Purity: 98%

Color and Shape: yellow solid

Molecular weight: 272.30g/mol

Ref: 54-OR1158

α-Naphthylflavone

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Color and Shape: Neat

Molecular weight: 272.30

Ref: TR-N372505

α-Naphthoflavone

CAS: 604-59-1

Alpha-naphthoflavone is a synthetic flavonoid, which is an aryl hydrocarbon receptor antagonist known for its interaction with cytochrome P450 enzymes. It is typically synthesized in laboratory settings and does not occur naturally. Alpha-naphthoflavone acts by competitively inhibiting the binding of ligands to the aryl hydrocarbon receptor (AhR) and modulating the activity of cytochrome P450 enzymes, particularly CYP1A1 and CYP1B1. This modulation is crucial in studying the metabolic pathways and the mechanism of enzyme induction or inhibition in xenobiotic metabolism.

Formula: C₁₉H₁₂O₂

Purity: Min. 98.0 Area-%

Molecular weight: 272.31 g/mol

Ref: 3D-N-1500

7,8-Benzoflavone

CAS: 604-59-1

7,8-Benzoflavone is a synthetic flavonoid compound, which is derived from the structural modification of naturally occurring flavones. It possesses significant biochemical activity attributed to its ability to act as a potent inhibitor of certain cytochrome P450 enzymes, particularly CYP1A1 and CYP1B1. By inhibiting these enzymes, 7,8-Benzoflavone modulates the metabolism of various xenobiotics, impacting the bioactivation or detoxification of potential carcinogens.

Formula: C₁₉H₁₂O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 272.3 g/mol

Ref: 3D-FB09432

a-Naphthoflavone extrapure AR, 98%

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Purity: min. 98%

Color and Shape: White to yellow, Crystalline powder, Clear

Molecular weight: 272.31

Ref: SR-57955

2-Phenyl-benzo[h]chromen-4-one

CAS: 604-59-1

Formula: C₁₉H₁₂O₂

Purity: 98%

Color and Shape: Solid, No data available.

Molecular weight: 272.303

Ref: 10-F058504