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CAS 6040-19-3

:

Cucurbitacin A

Description:
Cucurbitacin A is a triterpenoid compound primarily derived from plants in the Cucurbitaceae family, such as cucumbers and gourds. It is known for its bitter taste and has been studied for its potential pharmacological properties, including anti-cancer, anti-inflammatory, and anti-diabetic effects. The molecular structure of Cucurbitacin A features a complex tetracyclic framework, which contributes to its biological activity. It is typically found in low concentrations in various plant parts, including seeds and leaves. The compound exhibits a range of biological activities, including the inhibition of cell proliferation and induction of apoptosis in certain cancer cell lines. Additionally, Cucurbitacin A has been investigated for its potential to modulate various signaling pathways, making it a subject of interest in medicinal chemistry and natural product research. However, due to its toxicity at higher concentrations, careful consideration is necessary when exploring its therapeutic applications. Overall, Cucurbitacin A represents a fascinating area of study within phytochemistry and pharmacology.
Formula:C32H46O9
InChI:InChI=1/C32H46O9/c1-17(34)41-27(2,3)12-11-23(37)31(8,40)25-21(36)14-29(6)22-10-9-18-19(13-20(35)26(39)28(18,4)5)32(22,16-33)24(38)15-30(25,29)7/h9,11-12,19-22,25,33,35-36,40H,10,13-16H2,1-8H3/b12-11+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChI key:InChIKey=IHTCCHVMPGDDSL-IVNGUWCNSA-N
SMILES:C(O)[C@]12[C@]([C@@]3(C)[C@](C)(CC1=O)[C@@]([C@@](C(/C=C/C(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C3)[H])(CC=C4[C@]2(C[C@H](O)C(=O)C4(C)C)[H])[H]
Synonyms:
  • (2β,9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-19-norlanosta-5,23-diene-3,11,22-trione
  • 19-Nor-9β,10α-lanosta-5,23-diene-3,11,22-trione, 2β,16α,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate, (E)-
  • 19-Norlanosta-5,23-diene-3,11,22-trione, 2,16,20,25-tetrahydroxy-9-(hydroxymethyl)-, 25-acetate
  • 19-Norlanosta-5,23-diene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-, (2.beta.,9.beta.,10.alpha.,16.alpha.,23E)-
  • 19-Norlanosta-5,23-diene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-(hydroxymethyl)-, (2β,9β,10α,16α,23E)-
  • Cucurbitacin A
  • Cucurbitacine A
  • NSC 94743
  • (2S,4R,9beta,16alpha,23E)-2,16,20-trihydroxy-9-(hydroxymethyl)-10,14-dimethyl-1,11,22-trioxo-4,9-cyclo-9,10-secocholesta-5,23-dien-25-yl acetate
  • Cucurbitacin A USP/EP/BP
  • See more synonyms
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Found 5 products.
  • Cucurbitacin A
    Indagoo
    + Info

    Cucurbitacin A

    CAS:
    Formula:C32H46O9
    Purity:98%
    Molecular weight:574.7022

    Ref: IN-DA00EJ11

    5mg
    To inquire
  • Cucurbitacin A
    Targetmol
    + Info

    Cucurbitacin A

    CAS:
    <p>Cucurbitacin I, cytotoxic triterpenoid sterols isolated from plants, elicits the formation of actin/phospho-myosin II co-aggregates by stimulation of the RhoA/</p>
    Formula:C32H46O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:574.7

    Ref: TM-TN1533

  • Cucurbitacin A
    Biopurify
    + Info

    Cucurbitacin A

    CAS:
    Cucurbitacin A inhibits cancer growth in A-549 NSCLC cells by inducing apoptosis, targeting m-TOR/PI3K/Akt signalling pathway and G2/M cell cycle.
    Formula:C32H46O9
    Purity:95%~99%
    Color and Shape:Powder
    Molecular weight:574.711

    Ref: BP-BPF0324

    5mg
    529.00€
  • Cucurbitacin a
    Phytolab
    + Info

    Cucurbitacin a

    CAS:
    Acetic acid ester
    Formula:C32H46O9
    Purity:≥ 85.0 % (HPLC)
    Molecular weight:574.7

    Ref: 5G-84046

    5mg
    301.00€
    50mg
    2,452.00€
    250mg
    11,578.00€
    500mg
    21,793.00€
    1000mg
    40,861.00€
  • Cucurbitacin A
    Biosynth
    + Info

    Cucurbitacin A

    Controlled Product
    CAS:
    <p>Cucurbitacin A is a polyphenolic secondary metabolite that has been shown to have a variety of biological activities. It has been shown to inhibit HIV-1 replication and induce apoptosis in cancer cells. Cucurbitacin A also inhibits the growth of human prostate cancer cells by inhibiting the expression of proteins involved in cell proliferation, such as cyclin D1 and p27. Cucurbitacin A also has potent anticancer activity against a broad range of cancer cells including breast, lung, colon, leukemia, melanoma, and ovarian cancers. Moreover, cucurbitacin A shows promise for the treatment of heart disease because it has been shown to inhibit platelet aggregation. The chemical stability and chemical composition make cucurbitacin A an attractive candidate for use as a pharmaceutical preparation.</p>
    Formula:C32H46O9
    Purity:Min. 95%
    Molecular weight:574.71 g/mol

    Ref: 3D-GAA04019

    10mg
    863.00€
    25mg
    1,222.00€
    50mg
    1,954.00€