CAS 60467-72-3

1,8-Naphthyridine-3-carbonitrile, 1,2-dihydro-2-oxo-

Description:

1,8-Naphthyridine-3-carbonitrile, 1,2-dihydro-2-oxo- is a heterocyclic organic compound characterized by its bicyclic structure, which includes a naphthyridine moiety. This compound features a carbonitrile functional group and a diketone structure, contributing to its reactivity and potential applications in various chemical reactions. The presence of the carbonitrile group suggests that it may participate in nucleophilic addition reactions, while the diketone functionality can engage in condensation reactions. The compound is typically solid at room temperature and may exhibit moderate solubility in polar organic solvents. Its unique structure makes it of interest in medicinal chemistry, particularly for the development of pharmaceuticals, as naphthyridine derivatives are known for their biological activity. Additionally, the compound's properties, such as melting point, boiling point, and spectral characteristics (like NMR and IR), would be essential for its identification and characterization in laboratory settings. Overall, 1,8-Naphthyridine-3-carbonitrile, 1,2-dihydro-2-oxo- represents a valuable scaffold in organic synthesis and drug discovery.

Formula: C₉H₅N₃O

2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile

CAS: 60467-72-3

Formula: C₉H₅N₃O

Color and Shape: Solid

Molecular weight: 171.1555

Ref: IN-DA00F4BC

1,2-Dihydro-2-oxo-1,8-naphthyridine-3-carbonitrile

CAS: 60467-72-3

1,2-Dihydro-2-oxo-1,8-naphthyridine-3-carbonitrile

Purity: 95%

Molecular weight: 171.16g/mol

Ref: 54-OR61356

2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile

CAS: 60467-72-3

2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile is an experimental drug that acts as a 5HT3 receptor antagonist. It has been shown to inhibit the effects of serotonin in the ileum and also inhibits the binding of serotonin to 5HT3 receptors. 2-Oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile has been shown to be effective in animal models for conditions such as irritable bowel syndrome and nausea. This drug is a piperidine derivative that can be synthesized using microwave irradiation in a reaction with ethyl cyanoacetate or cyanoacetate. The 5HT3 receptor antagonists are used to treat nausea and vomiting caused by various conditions such as chemotherapy, general anaesthesia, and postoperative nausea and vomiting.

Formula: C₉H₅N₃O

Purity: Min. 95%

Molecular weight: 171.16 g/mol

Ref: 3D-KCA46772